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ENTPD4 blocking peptide

ENTPD4 Antibody (N-term) Blocking Peptide

Gene Names
ENTPD4; LAP70; LALP70; LYSAL1; UDPase; NTPDase-4
Synonyms
ENTPD4; ENTPD4 Antibody (N-term) Blocking Peptide; Ectonucleoside triphosphate diphosphohydrolase 4; NTPDase 4; Lysosomal apyrase-like protein of 70 kDa; Uridine-diphosphatase; UDPase; KIAA0392; LALP70; LYSAL1; ENTPD4 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
616
Cellular Location
Golgi apparatus membrane; Multi-pass membrane protein. Cytoplasmic vesicle, autophagosome membrane; Multi-pass membrane protein. Note: Localizes in the Golgi and autophagic vacuoles/lysosomes
Tissue Location
Ubiquitous. Highest expression in testis and lowest in bladder
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ENTPD4 blocking peptide
Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP, AMP, ADP, ATP and UMP are not substrates. Preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
69,421 Da
NCBI Official Full Name
Ectonucleoside triphosphate diphosphohydrolase 4
NCBI Official Synonym Full Names
ectonucleoside triphosphate diphosphohydrolase 4
NCBI Official Symbol
ENTPD4
NCBI Official Synonym Symbols
LAP70; LALP70; LYSAL1; UDPase; NTPDase-4
NCBI Protein Information
ectonucleoside triphosphate diphosphohydrolase 4
UniProt Protein Name
Ectonucleoside triphosphate diphosphohydrolase 4
UniProt Gene Name
ENTPD4
UniProt Synonym Gene Names
KIAA0392; LALP70; LYSAL1; NTPDase 4; UDPase
UniProt Entry Name
ENTP4_HUMAN

NCBI Description

This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. [provided by RefSeq, Sep 2011]

Uniprot Description

UDPase: an ectonucleoside triphosphate diphosphohydrolase. Hydrolyzes preferentially nucleoside 5'-diphosphates; nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP; AMP, ADP, ATP and UMP are not substrates. Two splice variant isoforms have been described. Preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes UTP and TTP

Protein type: EC 3.6.1.6; Nucleotide Metabolism - pyrimidine; Hydrolase; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p21.3

Cellular Component: integral to Golgi membrane; intracellular membrane-bound organelle

Molecular Function: uridine-diphosphatase activity

Biological Process: UDP catabolic process

Research Articles on ENTPD4

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Product Notes

The ENTPD4 entpd4 (Catalog #AAA9223214) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ENTPD4, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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