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TACC1 blocking peptide

TACC1 Antibody (N-term) Blocking Peptide

Gene Names
TACC1; Ga55
Synonyms
TACC1; TACC1 Antibody (N-term) Blocking Peptide; Transforming acidic coiled-coil-containing protein 1; Gastric cancer antigen Ga55; Taxin-1; KIAA1103; TACC1 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
805
Cellular Location
Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note: Nucleus during interphase. Weakly concentrated at centrosomes during mitosis and colocalizes with AURKC at the midbody during cytokinesis
Tissue Location
Isoform 1, isoform 3 and isoform 5 are ubiquitous. Isoform 2 is strongly expressed in the brain, weakly detectable in lung and colon, and overexpressed in gastric cancer Isoform 4 is not detected in normal tissues, but strong expression was found in gastric cancer tissues. Down-regulated in a subset of cases of breast cancer.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for TACC1 blocking peptide
Likely involved in the processes that promote cell division prior to the formation of differentiated tissues.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
17,815 Da
NCBI Official Full Name
Transforming acidic coiled-coil-containing protein 1
NCBI Official Synonym Full Names
transforming acidic coiled-coil containing protein 1
NCBI Official Symbol
TACC1
NCBI Official Synonym Symbols
Ga55
NCBI Protein Information
transforming acidic coiled-coil-containing protein 1
UniProt Protein Name
Transforming acidic coiled-coil-containing protein 1
UniProt Gene Name
TACC1
UniProt Synonym Gene Names
KIAA1103
UniProt Entry Name
TACC1_HUMAN

NCBI Description

This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]

Uniprot Description

TACC1: Likely involved in the processes that promote cell division prior to the formation of differentiated tissues. Belongs to the TACC family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Cell development/differentiation

Chromosomal Location of Human Ortholog: 8p11.22

Cellular Component: cytoplasm; intermediate filament cytoskeleton; microtubule cytoskeleton

Molecular Function: protein binding

Biological Process: cell proliferation; cerebral cortex development; microtubule cytoskeleton organization and biogenesis

Research Articles on TACC1

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Product Notes

The TACC1 tacc1 (Catalog #AAA9222561) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TACC1, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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