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ACCN4 Blocking Peptide | ASIC4 blocking peptide

ACCN4 Antibody (N-term) Blocking Peptide

Gene Names
ASIC4; ACCN4; BNAC4
Synonyms
ACCN4; ACCN4 Antibody (N-term) Blocking Peptide; Acid-sensing ion channel 4; ASIC4; Amiloride-sensitive cation channel 4; pituitary; ASIC4 blocking peptide
Ordering
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
647
Cellular Location
Membrane; Multi-pass membrane protein
Tissue Location
Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ASIC4 blocking peptide
Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
72,190 Da
NCBI Official Full Name
Acid-sensing ion channel 4
NCBI Official Synonym Full Names
acid sensing ion channel subunit family member 4
NCBI Official Symbol
ASIC4
NCBI Official Synonym Symbols
ACCN4; BNAC4
NCBI Protein Information
acid-sensing ion channel 4
UniProt Protein Name
Acid-sensing ion channel 4
Protein Family
UniProt Gene Name
ASIC4
UniProt Synonym Gene Names
ACCN4; ASIC4
UniProt Entry Name
ASIC4_HUMAN

NCBI Description

This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]

Uniprot Description

ASIC4: Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity. Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Transporter, ion channel; Channel, sodium; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: integral to plasma membrane

Molecular Function: ion channel activity; sodium ion transmembrane transporter activity

Biological Process: transport

Research Articles on ASIC4

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Product Notes

The ASIC4 asic4 (Catalog #AAA9221777) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ACCN4, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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