Rabbit STOM Polyclonal Antibody | anti-STOM antibody

STOM antibody

Cat. Num. AAA9411347

• Gene Names: STOM; BND7; EPB7; EPB72
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunofluorescence
• Purity: Antibodies were purified by affinity purification using immunogen.
• Synonyms: STOM; Polyclonal Antibody; STOM antibody; BND7; EPB7; EPB72; anti-STOM antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous level of total STOM antibody.
• Purity/Purification: Antibodies were purified by affinity purification using immunogen.
• Form/Format: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1.0 mg/ml (varies by lot)
• Sequence Length: 288

• Applicable Applications for anti-STOM antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Western blotting: 1:500 - 1:2000; Immunofluorescence: 1:50 - 1:200
• Immunogen Type: Recombinant Protein
• Immunogen Description: Recombinant protein of human STOM.
• Target Name: STOM
• Preparation and Storage: Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts of various tissues, using STOM antibody.)

Immunofluorescence (IF)

(Immunofluorescence analysis of HeLa cell using STOM antibody. Blue: DAPI for nuclear staining.)

Related Product Information for anti-STOM antibody

This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants.

Product Categories/Family for anti-STOM antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 38016911
• NCBI GeneID: 2040
• NCBI Accession #: NP_004090.4
• NCBI GenBank Nucleotide #: NM_004099.5
• UniProt Accession #: P27105; Q14087; Q15609; Q5VX96; Q96FK4; B1AM77
• Molecular Weight: 13,475 Da
• NCBI Official Full Name: erythrocyte band 7 integral membrane protein isoform a
• NCBI Official Synonym Full Names: stomatin
• NCBI Official Symbol: STOM
• NCBI Official Synonym Symbols: BND7; EPB7; EPB72
• NCBI Protein Information: erythrocyte band 7 integral membrane protein
• UniProt Protein Name: Erythrocyte band 7 integral membrane protein
• Protein Family: Stomatin
• UniProt Gene Name: STOM
• UniProt Synonym Gene Names: BND7; EPB72
• UniProt Entry Name: STOM_HUMAN

NCBI Description

This gene encodes a member of a highly conserved family of integral membrane proteins. The encoded protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of the encoded protein is associated with hereditary stomatocytosis, a form of hemolytic anemia. There is a pseudogene for this gene on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Uniprot Description

stomatin: Thought to regulate cation conductance. May regulate ASIC2 and ASIC3 gating. Belongs to the band 7/mec-2 family.

Protein type: Membrane protein, integral; Motility/polarity/chemotaxis; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 9q34.1

Cellular Component: extracellular space; cytoskeleton; membrane; mitochondrion; integral to plasma membrane; endoplasmic reticulum; cytoplasm; melanosome; vesicle; lipid raft

Molecular Function: protein homodimerization activity

Biological Process: protein homooligomerization

Disease: Overhydrated Hereditary Stomatocytosis