ACPL2 Blocking Peptide | PXYLP1 (HGNC:26303) blocking peptide
ACPL2 Antibody (Center) Blocking Peptide
Gene Names
PXYLP1; XYLP; ACPL2; HEL124
Synonyms
ACPL2; ACPL2 Antibody (Center) Blocking Peptide; 2-phosphoxylose phosphatase 1; 313-; Acid phosphatase-like protein 2; Xylosyl phosphatase; epididymis luminal protein 124 ; PXYLP1; PXYLP1 (HGNC:26303) blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
480
Cellular Location
Golgi apparatus membrane; Single-pass type II membrane protein. Note: Colocalizes to Golgi apparatus in a B3GAT3-dependent manner.
Tissue Location
Widely expressed. Strongly expressed in spleen, fetal liver, moderately in placenta, pancreas, kidney, thymus and colon.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for PXYLP1 (HGNC:26303) blocking peptide
Responsible for the 2-O-dephosphorylation of xylose in the glycosaminoglycan-protein linkage region of proteoglycans thereby regulating the amount of mature glycosaminoglycan (GAG) chains. Sulfated glycosaminoglycans (GAGs), including heparan sulfate and chondroitin sulfate, are synthesized on the so-called common GAG-protein linkage region (GlcUAbeta1-3Galbeta1-3Galbeta1- 4Xylbeta1-O-Ser) of core proteins, which is formed by the stepwise addition of monosaccharide residues by the respective specific glycosyltransferases. Xylose 2-O-dephosphorylation during completion of linkage region formation is a prerequisite for the initiation and efficient elongation of the repeating disaccharide region of GAG chains.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
53,257 Da
NCBI Official Full Name
2-phosphoxylose phosphatase 1
NCBI Official Synonym Full Names
2-phosphoxylose phosphatase 1
NCBI Official Symbol
PXYLP1
NCBI Official Synonym Symbols
XYLP; ACPL2; HEL124
NCBI Protein Information
2-phosphoxylose phosphatase 1
UniProt Protein Name
2-phosphoxylose phosphatase 1
UniProt Gene Name
PXYLP1
UniProt Entry Name
PXYP1_HUMAN
Uniprot Description
PXYLP1: Belongs to the histidine acid phosphatase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted; Phosphatase (non-protein); Motility/polarity/chemotaxis; EC 3.1.3.2
Chromosomal Location of Human Ortholog: 3q23
Cellular Component: Golgi apparatus
Molecular Function: phosphoric monoester hydrolase activity; protein binding
Biological Process: chondroitin sulfate proteoglycan biosynthetic process; glycosaminoglycan biosynthetic process
Research Articles on PXYLP1 (HGNC:26303)
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Product Notes
The PXYLP1 (HGNC:26303) pxylp1 (Catalog #AAA9221600) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ACPL2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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