GPHB5 blocking peptide
GPHB5 Antibody (C-term) Blocking Peptide
Gene Names
GPHB5; B5; GPB5; ZLUT1
Synonyms
GPHB5; GPHB5 Antibody (C-term) Blocking Peptide; Glycoprotein hormone beta-5; Thyrostimulin subunit beta; GPB5; ZLUT1; GPHB5 blocking peptide
Specificity
The synthetic peptide sequence used to generate the antibody was selected from the C-term region of GPHB5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
130
Cellular Location
Secreted.
Tissue Location
Highly expressed in brain and at low levels in pituitary. Also found in retina, testis and skin but not in pancreas, parotid, kidney, stomach, liver, colon, small intestine, thyroid, brain or adrenal gland. In pituitary, colocalizes with ACTH, suggesting that it is located in corticotrophs
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for GPHB5 blocking peptide
Stimulates the thyroid. Binds and activates THSR, leading to increased cAMP production.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
14,232 Da
NCBI Official Full Name
Glycoprotein hormone beta-5
NCBI Official Synonym Full Names
glycoprotein hormone beta 5
NCBI Official Symbol
GPHB5
NCBI Official Synonym Symbols
B5; GPB5; ZLUT1
NCBI Protein Information
glycoprotein hormone beta-5
UniProt Protein Name
Glycoprotein hormone beta-5
Protein Family
UniProt Gene Name
GPHB5
UniProt Synonym Gene Names
GPB5; ZLUT1
UniProt Entry Name
GPHB5_HUMAN
NCBI Description
GPHB5 is a cystine knot-forming polypeptide and a subunit of the dimeric glycoprotein hormone family (Hsu et al., 2002 [PubMed 12089349]).[supplied by OMIM, Mar 2008]
Uniprot Description
GPHB5: Stimulates the thyroid. Binds and activates THSR, leading to increased cAMP production. Belongs to the glycoprotein hormones subunit beta family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 14q23.2
Research Articles on GPHB5
Similar Products
Product Notes
The GPHB5 gphb5 (Catalog #AAA9219770) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "GPHB5, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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