RICH2 Blocking Peptide | ARHGAP44 blocking peptide
RICH2 Antibody (C-term) Blocking Peptide
Gene Names
ARHGAP44; RICH2; NPC-A-10
Synonyms
RICH2; RICH2 Antibody (C-term) Blocking Peptide; Rho GTPase-activating protein 44; NPC-A-10; Rho-type GTPase-activating protein RICH2; RhoGAP interacting with CIP4 homologs protein 2; RICH-2; ARHGAP44; KIAA0672; ARHGAP44 blocking peptide
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Sequence Length
818
Cellular Location
Cell projection, dendritic spine. Recycling endosome. Cell junction, synapse. Note: In CA1 hippocampal synapses, detected at both presynaptic and postsynaptic sites.
Tissue Location
Highly expressed in brain. Expressed at weak level in other tissues.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Related Product Information for ARHGAP44 blocking peptide
GTPase-activating protein (GAP) that stimulates the GTPase activity of Rho-type GTPases. Thereby, controls Rho-type GTPases cycling between their active GTP-bound and inactive GDP- bound states. May act as a GAP for CDC42 and RAC1. Endosomal recycling protein which, in association with SHANK3, is involved in synaptic plasticity. Promotes GRIA1 exocytosis from recycling endosomes and spine morphological changes associated to long-term potentiation.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
88,521 Da
NCBI Official Full Name
rho GTPase-activating protein 44 isoform 1
NCBI Official Synonym Full Names
Rho GTPase activating protein 44
NCBI Official Symbol
ARHGAP44
NCBI Official Synonym Symbols
RICH2; NPC-A-10
NCBI Protein Information
rho GTPase-activating protein 44
UniProt Protein Name
Rho GTPase-activating protein 44
Protein Family
UniProt Gene Name
ARHGAP44
UniProt Synonym Gene Names
KIAA0672; RICH2; RICH-2
UniProt Entry Name
RHG44_HUMAN
Uniprot Description
RICH2: GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1.
Protein type: GAPs, Rac/Rho; GAPs
Chromosomal Location of Human Ortholog: 17p12
Cellular Component: cytosol
Molecular Function: GTPase activator activity; phospholipid binding; protein binding
Biological Process: regulation of small GTPase mediated signal transduction
Research Articles on ARHGAP44
Similar Products
Product Notes
The ARHGAP44 arhgap44 (Catalog #AAA9217759) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "RICH2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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