TECTB blocking peptide

TECTB Antibody (N-term) Blocking peptide

• Synonyms: TECTB; TECTB Antibody (N-term) Blocking peptide; Beta-tectorin; TECTB blocking peptide

• Form/Format: Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
• Sequence Length: 329

• Cellular Location: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side Secreted, extracellular space, extracellular matrix. Note: Found in the non-collagenous matrix of the tectorial membrane
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Related Product Information for TECTB blocking peptide

One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.

NCBI and Uniprot Product Information

• NCBI GI #: 17158035
• NCBI GeneID: 6975
• NCBI Accession #: NP_478129.1
• NCBI GenBank Nucleotide #: NM_058222.2
• UniProt Accession #: Q96PL2; Q5VW53
• Molecular Weight: 36,956 Da
• NCBI Official Full Name: beta-tectorin
• NCBI Official Synonym Full Names: tectorin beta
• NCBI Official Symbol: TECTB
• NCBI Protein Information: beta-tectorin
• UniProt Protein Name: Beta-tectorin
• Protein Family: Beta-tectorin
• UniProt Gene Name: TECTB
• UniProt Entry Name: TECTB_HUMAN

NCBI Description

This gene encodes a non-collagenous glycoprotein component of the tectorial membrane, which covers the auditory hair cells in the cochlea of the inner ear. A similar protein in mouse functions in low-frequency hearing. [provided by RefSeq, Jul 2013]

Uniprot Description

TECTB: One of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 10q25-q26