Western Blot (WB)
(GABRR2 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GABRR2 antibody detected the GABRR2 protein (arrow).)
Rabbit anti-Human GABRR2 Polyclonal Antibody | anti-GABRR2 antibody
GABRR2 Antibody (N-term)
Western Blot (WB)
(GABRR2 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GABRR2 antibody detected the GABRR2 protein (arrow).)
Western Blot (WB)
(GABRR2 Antibody (N-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GABRR2 antibody detected the GABRR2 protein (arrow).)
mammalian brain where it acts at GABA receptors, which are
ligand-gated chloride channels. The protein encoded by this gene is
a member of the rho subunit family and is a component of the GABA
receptor complex.
Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Xuei, X., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (2), 418-427 (2010) :
Pattaro, C., et al. BMC Med. Genet. 11, 41 (2010) :
Osolodkin, D.I., et al. J. Mol. Graph. Model. 27(7):813-821(2009)
NCBI and Uniprot Product Information
NCBI Description
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA receptor complex. [provided by RefSeq, Jul 2008]
Uniprot Description
GABRR2: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-2 GABA receptor could play a role in retinal neurotransmission. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR2 sub-subfamily. 2 isoforms of the human protein are produced by alternative initiation.
Protein type: Membrane protein, multi-pass; Transporter, ion channel; Membrane protein, integral; Transporter
Chromosomal Location of Human Ortholog: 6q15
Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction
Molecular Function: protein domain specific binding; chloride channel activity; GABA-A receptor activity; extracellular ligand-gated ion channel activity
Biological Process: synaptic transmission; visual perception; transport; signal transduction; transmembrane transport; gamma-aminobutyric acid signaling pathway
Research Articles on GABRR2
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Product Notes
The GABRR2 gabrr2 (Catalog #AAA9214869) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 37-65. The GABRR2 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GABRR2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the GABRR2 gabrr2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GABRR2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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