Rabbit anti-Human OTUD1 Polyclonal Antibody | anti-OTUD1 antibody
OTUD1 Antibody (Center)
Western Blot (WB)
(OTUD1 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the OTUD1 antibody detected the OTUD1 protein (arrow).)
Immunohistochemistry (IHC)
(OTUD1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTUD1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
proteases that specifically cleave ubiquitin (MIM 191339) linkages,
negating the action of ubiquitin ligases. DUBA7 belongs to a DUB
subfamily characterized by an ovarian tumor (OTU) domain.[supplied
by OMIM].
Kayagaki, N., et al. Science 318(5856):1628-1632(2007)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
Makarova, K.S., et al. Trends Biochem. Sci. 25(2):50-52(2000)
NCBI and Uniprot Product Information
NCBI Description
Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. DUBA7 belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008]
Uniprot Description
OTUD1: Deubiquitinating enzyme that specifically hydrolyzes 'Lys-63'-linked polyubiquitin to monoubiquitin
Protein type: EC 3.4.19.12; Ubiquitin-specific protease
Chromosomal Location of Human Ortholog: 10p12.2
Molecular Function: ubiquitin-specific protease activity
Biological Process: proteolysis
Research Articles on OTUD1
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Product Notes
The OTUD1 otud1 (Catalog #AAA9213472) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 282-311. The OTUD1 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's OTUD1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the OTUD1 otud1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OTUD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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