Western Blot (WB)
(Western blot analysis of GUCY1A3 (arrow) using GUCY1A3 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GUCY1A3 gene (Lane 2) (Origene Technologies).)
Rabbit anti-Human Guanylyl Cyclase alpha 1 (GUCY1A3) Polyclonal Antibody | anti-GUCY1A3 antibody
Guanylyl Cyclase alpha 1 (GUCY1A3) Antibody (N-term)
Western Blot (WB)
(Western blot analysis of GUCY1A3 (arrow) using GUCY1A3 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GUCY1A3 gene (Lane 2) (Origene Technologies).)
Western Blot (WB)
(Western blot analysis of GUCY1A3 (arrow) using GUCY1A3 Antibody (N-term). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GUCY1A3 gene (Lane 2) (Origene Technologies).)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Western Blot (WB)
(Western blot analysis of anti-GUCY1A3 Pab in mouse brain tissue lysate (35ug/lane). GUCY1A3(arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of anti-GUCY1A3 Pab in mouse brain tissue lysate (35ug/lane). GUCY1A3(arrow) was detected using the purified Pab.)
Zhou, Y., et al., Gene 245(2):319-328 (2000).
Papapetropoulos, A., et al., J. Cell. Physiol. 167(2):213-221 (1996).
Giuili, G., et al., Hum. Genet. 91(3):257-260 (1993).
Giuili, G., et al., FEBS Lett. 304(1):83-88 (1992).
NCBI and Uniprot Product Information
NCBI Description
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Uniprot Description
GUCY1A3: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Protein type: Nucleotide Metabolism - purine; Receptor, misc.; Lyase; EC 4.6.1.2; Guanylyl cyclase
Chromosomal Location of Human Ortholog: 4q31.1-q31.2
Cellular Component: guanylate cyclase complex, soluble
Molecular Function: guanylate cyclase activity; GTP binding; heme binding; receptor activity
Biological Process: cGMP biosynthetic process; relaxation of vascular smooth muscle; positive regulation of cGMP biosynthetic process; blood circulation; regulation of blood pressure; blood coagulation; nitric oxide mediated signal transduction; response to defense-related host nitric oxide production
Disease: Moyamoya Disease 6 With Achalasia
Research Articles on GUCY1A3
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Product Notes
The GUCY1A3 gucy1a3 (Catalog #AAA9212649) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 269-300. The Guanylyl Cyclase alpha 1 (GUCY1A3) Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Guanylyl Cyclase alpha 1 (GUCY1A3) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC). WB~~1:1000. Researchers should empirically determine the suitability of the GUCY1A3 gucy1a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Guanylyl Cyclase alpha 1 (GUCY1A3), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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