Western Blot (WB)
(TRPC7 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TRPC7 antibody detected the TRPC7 protein (arrow).)
Rabbit anti-Human TRPC7 Polyclonal Antibody | anti-TRPC7 antibody
TRPC7 Antibody (C-term)
Gene Names
TRPC7; TRP7
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TRPC7; Polyclonal Antibody; TRPC7 Antibody (C-term); Short transient receptor potential channel 7; TrpC7; Transient receptor protein 7; TRP-7; hTRP7; TRP7; anti-TRPC7 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TRPC7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 834-862 amino acids from the C-terminal region of human TRPC7.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
834-862
Sequence Length
746
Applicable Applications for anti-TRPC7 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(TRPC7 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TRPC7 antibody detected the TRPC7 protein (arrow).)
Western Blot (WB)
(TRPC7 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the TRPC7 antibody detected the TRPC7 protein (arrow).)
Related Product Information for anti-TRPC7 antibody
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.
Product Categories/Family for anti-TRPC7 antibody
References
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Miyagi, K., et al. J. Biol. Chem. 284(49):34400-34412(2009)
Graubert, T.A., et al. PLoS ONE 4 (2), E4583 (2009) :
Abed, E., et al. Cell Prolif. 40(6):849-865(2007)
Numaga, T., et al. Handb Exp Pharmacol 179, 143-151 (2007) :
Miyagi, K., et al. J. Biol. Chem. 284(49):34400-34412(2009)
Graubert, T.A., et al. PLoS ONE 4 (2), E4583 (2009) :
Abed, E., et al. Cell Prolif. 40(6):849-865(2007)
Numaga, T., et al. Handb Exp Pharmacol 179, 143-151 (2007) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
99562
NCBI Official Full Name
short transient receptor potential channel 7 isoform 3
NCBI Official Synonym Full Names
transient receptor potential cation channel, subfamily C, member 7
NCBI Official Symbol
TRPC7
NCBI Official Synonym Symbols
TRP7
NCBI Protein Information
short transient receptor potential channel 7
UniProt Protein Name
Short transient receptor potential channel 7
Protein Family
UniProt Gene Name
TRPC7
UniProt Synonym Gene Names
TRP7; TrpC7; TRP-7; hTRP7
UniProt Entry Name
TRPC7_HUMAN
Uniprot Description
TRPC7: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG). May also be activated by intracellular calcium store depletion. Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC7 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Channel, calcium; Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 5q31.1
Cellular Component: cis-Golgi network; perinuclear region of cytoplasm; integral to membrane; plasma membrane; nuclear envelope
Molecular Function: protein binding; calcium channel activity
Biological Process: axon guidance; platelet activation; manganese ion transport; blood coagulation; transmembrane transport
Research Articles on TRPC7
Similar Products
Product Notes
The TRPC7 trpc7 (Catalog #AAA9211755) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 834-862. The TRPC7 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TRPC7 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the TRPC7 trpc7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TRPC7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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