Western Blot (WB)
(STX1B Antibody (N-term) western blot analysis in SH-SY5Y cell line lysates (35ug/lane).This demonstrates the STX1B antibody detected the STX1B protein (arrow).)
Rabbit STX1B Polyclonal Antibody | anti-STX1B antibody
STX1B Antibody (N-term)
Western Blot (WB)
(STX1B Antibody (N-term) western blot analysis in SH-SY5Y cell line lysates (35ug/lane).This demonstrates the STX1B antibody detected the STX1B protein (arrow).)
Western Blot (WB)
(STX1B Antibody (N-term) western blot analysis in SH-SY5Y cell line lysates (35ug/lane).This demonstrates the STX1B antibody detected the STX1B protein (arrow).)
Gastaldi M., et al. Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to a family of proteins thought to play a role in the exocytosis of synaptic vesicles. Vesicle exocytosis releases vesicular contents and is important to various cellular functions. For instance, the secretion of transmitters from neurons plays an important role in synaptic transmission. After exocytosis, the membrane and proteins from the vesicle are retrieved from the plasma membrane through the process of endocytosis. Mutations in this gene have been identified as one cause of fever-associated epilepsy syndromes. A possible link between this gene and Parkinson's disease has also been suggested. [provided by RefSeq, Jan 2015]
Uniprot Description
STX1B: a type IV membrane protein that may be involved in docking of synaptic vesicles at presynaptic active zones.
Protein type: Membrane protein, integral; Vesicle
Chromosomal Location of Human Ortholog: 16p11.2
Cellular Component: SNARE complex; synaptic vesicle; membrane; integral to membrane; plasma membrane; endomembrane system; microtubule organizing center; spindle; cytosol; nucleus
Molecular Function: protein domain specific binding; SNAP receptor activity; SNARE binding; protein kinase binding
Biological Process: synaptic vesicle fusion to presynaptic membrane; intracellular protein transport; vesicle docking; regulation of gene expression; pathogenesis; positive regulation of neurotransmitter secretion; synaptic vesicle docking during exocytosis
Disease: Generalized Epilepsy With Febrile Seizures Plus, Type 9
Research Articles on STX1B
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Product Notes
The STX1B stx1b (Catalog #AAA9211083) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The STX1B Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's STX1B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the STX1B stx1b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STX1B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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