Western Blot (WB)
(KCTD8 Antibody (C-term) western blot analysis in mouse liver and heart tissue lysates (35ug/lane).This demonstrates the KCTD8 antibody detected the KCTD8 protein (arrow).)
Rabbit anti-Human, mouse KCTD8 Polyclonal Antibody | anti-KCTD8 antibody
KCTD8 Antibody (C-term)
Reactivity
Human, mouse
Applications
Western Blot, ELISA, Immunohistochemistry
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
KCTD8; Polyclonal Antibody; KCTD8 Antibody (C-term); BTB/POZ domain-containing protein KCTD8; anti-KCTD8 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This KCTD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 434-462 amino acids from the C-terminal region of human KCTD8.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
434-462
Sequence Length
473
Applicable Applications for anti-KCTD8 antibody
Western Blot (WB), ELISA (EIA), Immunohistochemistry-Paraffin (IHC-p)
Application Notes
WB~~1:1000
IHC-p~~1:50~100
IHC-p~~1:50~100
Cellular Location
Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse, postsynaptic cell membrane
Function
Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Western Blot (WB)
(KCTD8 Antibody (C-term) western blot analysis in mouse liver and heart tissue lysates (35ug/lane).This demonstrates the KCTD8 antibody detected the KCTD8 protein (arrow).)
Western Blot (WB)
(KCTD8 Antibody (C-term) western blot analysis in mouse liver and heart tissue lysates (35ug/lane).This demonstrates the KCTD8 antibody detected the KCTD8 protein (arrow).)
Immunohistochemistry (IHC)
(KCTD8 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCTD8 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(KCTD8 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of KCTD8 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Product Categories/Family for anti-KCTD8 antibody
References
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
52440
NCBI Official Full Name
BTB/POZ domain-containing protein KCTD8
NCBI Official Synonym Full Names
potassium channel tetramerization domain containing 8
NCBI Official Symbol
KCTD8
NCBI Protein Information
BTB/POZ domain-containing protein KCTD8
UniProt Protein Name
BTB/POZ domain-containing protein KCTD8
Protein Family
UniProt Gene Name
KCTD8
UniProt Entry Name
KCTD8_HUMAN
Uniprot Description
KCTD8: Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization.
Chromosomal Location of Human Ortholog: 4p13
Cellular Component: presynaptic membrane; postsynaptic membrane; cell junction; receptor complex
Biological Process: protein homooligomerization; regulation of G-protein coupled receptor protein signaling pathway
Research Articles on KCTD8
Similar Products
Product Notes
The KCTD8 kctd8 (Catalog #AAA9210853) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 434-462. The KCTD8 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KCTD8 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry-Paraffin (IHC-p). WB~~1:1000 IHC-p~~1:50~100. Researchers should empirically determine the suitability of the KCTD8 kctd8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KCTD8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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