Western Blot (WB)
(IGSF1 Antibody (C-term)(MBS9207257) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the IGSF1 antibody detected the IGSF1 protein (arrow).)
Rabbit IGSF1 Polyclonal Antibody | anti-IGSF1 antibody
IGSF1 Antibody (C-term)
Predicted Reactivity: Rat
Predicted Reactivity: Rat
IHC-P~~1:50~100
Western Blot (WB)
(IGSF1 Antibody (C-term)(MBS9207257) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the IGSF1 antibody detected the IGSF1 protein (arrow).)
Western Blot (WB)
(IGSF1 Antibody (C-term)(MBS9207257) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the IGSF1 antibody detected the IGSF1 protein (arrow).)
Immunohistochemistry (IHC)
(IGSF1 antibody (C-term)(MBS9207257) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IGSF1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(IGSF1 antibody (C-term)(MBS9207257) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IGSF1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
domain-containing superfamily. Proteins in this superfamily contain
varying numbers of immunoglobulin-like domains and are thought to
participate in the regulation of interactions between cells.
Multiple transcript variants encoding different isoforms have been
found for this gene.
Nakayama, M., et al. Genome Res. 12(11):1773-1784(2002)
Tanaka, S., et al. J. Mol. Endocrinol. 28(1):33-44(2002)
Gui, Y., et al. J. Clin. Endocrinol. Metab. 86(5):2104-2110(2001)
Chapman, S.C., et al. Mol. Endocrinol. 15(4):668-679(2001)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the immunoglobulin-like domain-containing superfamily. Proteins in this superfamily contain varying numbers of immunoglobulin-like domains and are thought to participate in the regulation of interactions between cells. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2010]
Uniprot Description
IGSF1: Seems to be a coreceptor in inhibin signaling, but seems not to be a high-affinity inhibin receptor. Antagonizes activin A signaling in the presence or absence of inhibin B. Necessary to mediate a specific antagonistic effect of inhibin B on activin-stimulated transcription. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, misc.; Immunoglobulin superfamily; Motility/polarity/chemotaxis; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: Xq25
Cellular Component: membrane; extracellular region; integral to membrane
Molecular Function: protein binding; coreceptor activity; receptor activity
Biological Process: regulation of transcription, DNA-dependent; signal transduction
Disease: Hypothyroidism, Central, And Testicular Enlargement
Research Articles on IGSF1
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Product Notes
The IGSF1 igsf1 (Catalog #AAA9207257) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1270-1297. The IGSF1 Antibody (C-term) reacts with Human, Mouse Predicted Reactivity: Rat and may cross-react with other species as described in the data sheet. AAA Biotech's IGSF1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), ELISA (EIA). WB~~1:1000 IHC-P~~1:50~100. Researchers should empirically determine the suitability of the IGSF1 igsf1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IGSF1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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