Western Blot (WB)
(Western blot analysis of ELOVL5 Antibody (C-term) in Hela cell line lysates (35ug/lane). ELOVL5 (arrow) was detected using the purified Pab.)
Rabbit ELOVL5 Polyclonal Antibody | anti-ELOVL5 antibody
ELOVL5 Antibody (C-term)
Western Blot (WB)
(Western blot analysis of ELOVL5 Antibody (C-term) in Hela cell line lysates (35ug/lane). ELOVL5 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of ELOVL5 Antibody (C-term) in Hela cell line lysates (35ug/lane). ELOVL5 (arrow) was detected using the purified Pab.)
Flow Cytometry (FC/FACS)
(ELOVL5 Antibody (C-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(ELOVL5 Antibody (C-term) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Barragan, I., et al. Int. J. Mol. Med. 16(6):1163-1167(2005)
NCBI and Uniprot Product Information
NCBI Description
This gene belongs to the ELO family. It is highly expressed in the adrenal gland and testis, and encodes a multi-pass membrane protein that is localized in the endoplasmic reticulum. This protein is involved in the elongation of long-chain polyunsaturated fatty acids. Mutations in this gene have been associated with spinocerebellar ataxia-38 (SCA38). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
Uniprot Description
ELOVL5: Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. Belongs to the ELO family.
Protein type: Lipid Metabolism - unsaturated fatty acid biosynthesis; Membrane protein, multi-pass; EC 2.3.1.199; Membrane protein, integral
Chromosomal Location of Human Ortholog: 6p12.1
Cellular Component: endoplasmic reticulum membrane; cell soma; membrane; endoplasmic reticulum; dendrite; integral to membrane
Molecular Function: protein binding; fatty acid elongase activity
Biological Process: unsaturated fatty acid metabolic process; very-long-chain fatty acid biosynthetic process; linoleic acid metabolic process; unsaturated fatty acid biosynthetic process; triacylglycerol biosynthetic process; cellular lipid metabolic process
Disease: Spinocerebellar Ataxia 38
Research Articles on ELOVL5
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Product Notes
The ELOVL5 elovl5 (Catalog #AAA9204766) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 271-299. The ELOVL5 Antibody (C-term) reacts with Human (Predicted Reactivity: Monkey) and may cross-react with other species as described in the data sheet. AAA Biotech's ELOVL5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the ELOVL5 elovl5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ELOVL5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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