Rabbit GRSF1 Polyclonal Antibody | anti-GRSF1 antibody

GRSF1 Antibody (Center)

Cat. Num. AAA9203495

• Reactivity: Human (Predicted Reactivity: Mouse)
• Applications: Western Blot, ELISA
• Purity: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Synonyms: GRSF1; Polyclonal Antibody; GRSF1 Antibody (Center); G-rich sequence factor 1; GRSF-1; anti-GRSF1 antibody

• Host: Rabbit
• Reactivity: Human (Predicted Reactivity: Mouse)
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This GRSF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-333 amino acids from the Central region of human GRSF1.
• Purity/Purification: Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
• Concentration: Vial Concentration: 0.5 (varies by lot)
• Sequence Positions: 307-333
• Sequence Length: 318

• Applicable Applications for anti-GRSF1 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB~~1:1000
• Antigen Type: Synthetic Peptide
• Antigen Source: HUMAN
• Preparation and Storage: Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(GRSF1 Antibody (Center) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the GRSF1 antibody detected the GRSF1 protein (arrow).)

Related Product Information for anti-GRSF1 antibody

The protein encoded by this gene is a cellular protein
that binds RNAs containing the G-rich element. The protein is
localized in the cytoplasm, and has been shown to stimulate
translation of viral mRNAs in vitro. Multiple transcript variants
encoding different isoforms have been found for this gene.

References

Kash, J.C., et al. J. Virol. 76(20):10417-10426(2002)
Park, Y.W., et al. Proc. Natl. Acad. Sci. U.S.A. 96(12):6694-6699(1999)
Banga, S.S., et al. Cytogenet. Cell Genet. 73(4):295-296(1996)
Qian, Z., et al. Nucleic Acids Res. 22(12):2334-2343(1994)

NCBI and Uniprot Product Information

• NCBI GI #: 149193319
• NCBI GeneID: 2926
• NCBI Accession #: NP_001091947.1; NP_002083.3
• NCBI GenBank Nucleotide #: NM_001098477.1
• UniProt Accession #: Q12849; Q4W5S5; Q6ZST3; Q8IWD6; Q8NBD2; B3KPW0
• Molecular Weight: 53126
• NCBI Official Full Name: G-rich sequence factor 1 isoform 2
• NCBI Official Synonym Full Names: G-rich RNA sequence binding factor 1
• NCBI Official Symbol: GRSF1
• NCBI Protein Information: G-rich sequence factor 1
• UniProt Protein Name: G-rich sequence factor 1
• Protein Family: G-rich sequence factor
• UniProt Gene Name: GRSF1
• UniProt Synonym Gene Names: GRSF-1
• UniProt Entry Name: GRSF1_HUMAN

NCBI Description

The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

GRSF1: Binds RNAs containing the 14 base G-rich element. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: RNA-binding

Chromosomal Location of Human Ortholog: 4q13

Cellular Component: mitochondrion; cytoplasm

Molecular Function: mRNA binding; RNA binding; nucleotide binding

Biological Process: anterior/posterior pattern formation; morphogenesis of embryonic epithelium; tRNA processing; mRNA polyadenylation