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Western Blot (WB) (Mouse Tshz1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the Mouse Tshz1 antibody detected the Mouse Tshz1 protein (arrow).)

Rabbit anti-Human, mouse Tshz1 Polyclonal Antibody | anti-Tshz1 antibody

Mouse Tshz1 Antibody (Center)

Gene Names
Tshz1; Tsh1; Mtsh1; NY-CO-33; Sdccag33; mKIAA4206; teashirt1; D18Bwg1409e; 5730407I04Rik
Reactivity
Human, mouse
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Tshz1; Polyclonal Antibody; Mouse Tshz1 Antibody (Center); Teashirt homolog 1; Serologically defined colon cancer antigen 3 homolog; Kiaa4206; Sdccag33; Tsh1; anti-Tshz1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Tshz1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 639-665 amino acids from the Central region of mouse Tshz1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
639-665
Sequence Length
1,084
Applicable Applications for anti-Tshz1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
MOUSE
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Mouse Tshz1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the Mouse Tshz1 antibody detected the Mouse Tshz1 protein (arrow).)

Western Blot (WB) (Mouse Tshz1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the Mouse Tshz1 antibody detected the Mouse Tshz1 protein (arrow).)
Related Product Information for anti-Tshz1 antibody
Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential).
Product Categories/Family for anti-Tshz1 antibody
References
Endoh-Yamagami, S., et al. Dev. Biol. 340(1):41-53(2010)
Jenkins, D., et al. Nephrol. Dial. Transplant. 25(1):54-60(2010)
Carney, R.S., et al. Cereb. Cortex 19(4):745-759(2009)
Kajiwara, Y., et al. PLoS ONE 4 (4), E5071 (2009) :
Core, N., et al. Dev. Biol. 308(2):407-420(2007)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
118567
NCBI Official Full Name
teashirt homolog 1
NCBI Official Synonym Full Names
teashirt zinc finger family member 1
NCBI Official Symbol
Tshz1
NCBI Official Synonym Symbols
Tsh1; Mtsh1; NY-CO-33; Sdccag33; mKIAA4206; teashirt1; D18Bwg1409e; 5730407I04Rik
NCBI Protein Information
teashirt homolog 1
UniProt Protein Name
Teashirt homolog 1
Protein Family
UniProt Gene Name
Tshz1
UniProt Synonym Gene Names
Kiaa4206; Sdccag33; Tsh1
UniProt Entry Name
TSH1_MOUSE

Uniprot Description

TSHZ1: Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). Defects in TSHZ1 are the cause of congenital aural atresia (CAA). A rare anomaly of the ear that involves some degree of failure of the development of the external auditory canal. The malformation can also involve the tympanic membrane, ossicles and middle ear space. The inner ear development is most often normal. Different CAA forms are known. CAA type I is characterized by bony or fibrous atresia of the lateral part of the external auditory canal and an almost normal medial part and middle ear. CAA type II is the most frequent type and is characterized by partial or total aplasia of the external auditory canal. CAA type IIA involves an external auditory canal with either complete bony atresia of the medial part or partial aplasia that ends blindly in a fistula leading to a rudimentary tympanic membrane. CAA type IIB is characterized by bony stenosis of the total length of the external auditory canal. CAA type III involves bony atresia of the external auditory canal and a very small or absent middle-ear cavity. Belongs to the teashirt C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; C2H2-type zinc finger protein; Transcription factor

Cellular Component: nucleus

Molecular Function: protein binding; DNA binding; metal ion binding

Biological Process: anterior/posterior pattern formation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; regulation of gene expression; multicellular organismal development; middle ear morphogenesis; soft palate development

Research Articles on Tshz1

Similar Products

Product Notes

The Tshz1 tshz1 (Catalog #AAA9203441) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 639-665. The Mouse Tshz1 Antibody (Center) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Tshz1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Tshz1 tshz1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tshz1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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