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Typical Testing Data/Standard Curve (for reference only)

Human thrombospondin 2 ELISA Kit | THBS2 elisa kit

Human Thrombospondin-2, THBS2 ELISA Kit

Gene Names
THBS2; TSP2
Reactivity
Human
Synonyms
thrombospondin 2; Human Thrombospondin-2; THBS2 ELISA Kit; Human Thrombospondin-2 (THBS2) ELISA kit; TSP2; ; Human Thrombospondin-2 (THBS2); THBS2 elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Specificity
This assay has high sensitivity and excellent specificity for detection of human THBS2. No significant cross-reactivity or interference between human THBS2 and analogues was observed.
Sequence Length
1172
Samples
Serum, plasma, tissue homogenates
Assay Type
Quantitative Sandwich
Detection Range
1.562 ng/ml-100 ng/ml
Sensitivity
< 1.191 ng/ml
Intra-assay Precision
Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision
Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
Preparation and Storage
Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for THBS2 elisa kit
Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for THBS2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any THBS2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for THBS2 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of THBS2 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
129,991 Da
NCBI Official Full Name
thrombospondin-2
NCBI Official Synonym Full Names
thrombospondin 2
NCBI Official Symbol
THBS2
NCBI Official Synonym Symbols
TSP2
NCBI Protein Information
thrombospondin-2
UniProt Protein Name
Thrombospondin-2
Protein Family
UniProt Gene Name
THBS2
UniProt Synonym Gene Names
TSP2
UniProt Entry Name
TSP2_HUMAN

NCBI Description

The protein encoded by this gene belongs to the thrombospondin family. It is a disulfide-linked homotrimeric glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein has been shown to function as a potent inhibitor of tumor growth and angiogenesis. Studies of the mouse counterpart suggest that this protein may modulate the cell surface properties of mesenchymal cells and be involved in cell adhesion and migration. [provided by RefSeq, Jul 2008]

Uniprot Description

THBS2: Adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. Ligand for CD36 mediating antiangiogenic properties. Genetic variations in THBS2 may be a cause of susceptibility to intervertebral disk disease (IDD); also known as lumbar disk herniation (LDH). IDD is one of the most common musculo-skeletal disorders and the predominant cause of low-back pain and unilateral leg pain. Belongs to the thrombospondin family.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: extracellular region; basement membrane

Molecular Function: heparin binding; protein binding; calcium ion binding

Biological Process: positive regulation of synaptogenesis; negative regulation of angiogenesis; cell adhesion

Disease: Intervertebral Disc Disease

Research Articles on THBS2

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Product Notes

The Human THBS2 thbs2 (Catalog #AAA915454) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA915454 ELISA Kit recognizes Human THBS2. It is sometimes possible for the material contained within the vial of "thrombospondin 2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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