Hemagglutinin (HA) Recombinant Protein | HA recombinant protein
Recombinant Influenza A virus Hemagglutinin (HA), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Hemagglutinin (HA); Recombinant Influenza A virus Hemagglutinin (HA); partial; HA recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
18-529aa, Partial
Sequence
DTICVGYHANNSTDTVDTILEKNVTVTHSVNLLENSHNGKLCSLNGKIPLQLGNCNVAGWILGNPKCDLLLTANSWSYIIETSNSKNGACYPGEFADYEELKEQLSTVSSFERFEIFPKATSWPNHDTTRGTTVACSHSGANSFYRNLLWIVKKGNSYPKLSKSYTNNKGKEVLVIWGVHHPPTESDQQTLYQNNHTYVSVGSSKYYKRFTPEIVARPKVREQAGRMNYYWTLLDQGDTITFEATGNLIAPWHAFALKKGSSSGIMRSDAQVHNCTTKCQTPHGALKGNLPFQNVHPVTIGKCPKYVKSTQLRMATGLRNIPSIQSRGLFGAIAGFIEGGWTGMVDGWYGYHHRNEQGSGYAADQKSTQIAIDGISNKVNSVIEKMNIQFTSVGKEFNSLEKRMENLNKKVDDGFLDVWTYNAELLILLENERTLDFHDLNVKNLYEKVKSQLRNNAKEIGNGCFEFYHKCDNECMESVKNGTYNYPKYSEESKLNREEIDGVKLESMGIHQ
Species
Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
Relevance
Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20 degree C/-80 degree C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Product Categories/Family for HA recombinant protein
NCBI and Uniprot Product Information
Similar Products
Product Notes
The HA (Catalog #AAA9018644) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 18-529aa, Partial. The amino acid sequence is listed below: DTICVGYHAN NSTDTVDTIL EKNVTVTHSV NLLENSHNGK LCSLNGKIPL QLGNCNVAGW ILGNPKCDLL LTANSWSYII ETSNSKNGAC YPGEFADYEE LKEQLSTVSS FERFEIFPKA TSWPNHDTTR GTTVACSHSG ANSFYRNLLW IVKKGNSYPK LSKSYTNNKG KEVLVIWGVH HPPTESDQQT LYQNNHTYVS VGSSKYYKRF TPEIVARPKV REQAGRMNYY WTLLDQGDTI TFEATGNLIA PWHAFALKKG SSSGIMRSDA QVHNCTTKCQ TPHGALKGNL PFQNVHPVTI GKCPKYVKST QLRMATGLRN IPSIQSRGLF GAIAGFIEGG WTGMVDGWYG YHHRNEQGSG YAADQKSTQI AIDGISNKVN SVIEKMNIQF TSVGKEFNSL EKRMENLNKK VDDGFLDVWT YNAELLILLE NERTLDFHDL NVKNLYEKVK SQLRNNAKEI GNGCFEFYHK CDNECMESVK NGTYNYPKYS EESKLNREEI DGVKLESMGI HQ. It is sometimes possible for the material contained within the vial of "Hemagglutinin (HA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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