Rabbit SUVR2 Polyclonal Antibody | anti-SUVR2 antibody

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SUVR2 Polyclonal Antibody

• Gene Names: SUVR2; MRH10.10; MRH10_10; SDG18; SET DOMAIN PROTEIN 18
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: SUVR2; Polyclonal Antibody; Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) SUVR2 Polyclonal Antibody; SUVR2 Antibody; Probable inactive histone-lysine N-methyltransferase SUVR2; Protein SET DOMAIN GROUP 18; Suppressor of variegation 3-9-related protein 2; Su(var)3-9-related protein 2; SUVR2 SDG18 SET18 At5g43990 MRH10.10; anti-SUVR2 antibody

• Host: Rabbit
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-SUVR2 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Arabidopsis thaliana SUVR2 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 145334713
• NCBI GeneID: 834422
• NCBI Accession #: NP_001078702.1
• NCBI GenBank Nucleotide #: NM_001085233.2
• UniProt Accession #: Q9FNC7; Q0WKU5; Q941L4
• Molecular Weight: 79,363 Da
• NCBI Official Full Name: SET-domain containing protein lysine methyltransferase family protein
• NCBI Official Symbol: SUVR2
• NCBI Official Synonym Symbols: MRH10.10; MRH10_10; SDG18; SET DOMAIN PROTEIN 18
• NCBI Protein Information: SET-domain containing protein lysine methyltransferase family protein
• UniProt Protein Name: Probable inactive histone-lysine N-methyltransferase SUVR2
• Protein Family: Probable inactive histone-lysine N-methyltransferase
• UniProt Gene Name: SUVR2
• UniProt Synonym Gene Names: SDG18; SET18; Su(var)3-9-related protein 2

NCBI Description

Encodes SUVR2, one of the four closely related Arabidopsis SUVR proteins that belong to the SU(VAR)3-9 subgroup of SET-domain proteins. Proteins containing the evolutionarily conserved SET domain are involved in regulation of eukaryotic gene expression and chromatin structure through their histone lysine methyltransferase (HMTase) activity. SUVR1, SUVR2 and SUVR4 proteins contain a novel domain at their N-terminus, and a SUVR specific region preceding the SET domain. Localized to the nucleolus, maybe involved in regulation of rRNA expression.

Uniprot Description

Probable inactive histone-lysine methyltransferase that acts as regulator of transctiptional gene silencing independently of histone H3K9 methylation. Contributes to transcriptional gene silencing at RNA-directed DNA methylation (RdDM) target loci but also at RdDM-independent target loci. Forms a complex with SUVR1 and associates with the SNF2-related chromatin-remodeling proteins CHR19, CHR27, and CHR28, thereby mediating nucleosome positioning and transcriptional silencing. Does not possess histone-lysine methyltransferase activity in vitro, and the conserved catalytic sites of SUVR2 are dispensable for its function in transcriptional gene silencing.