Rabbit NERD Polyclonal Antibody | anti-NERD antibody

Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) NERD Polyclonal Antibody

• Gene Names: NERD; F16F14.1; F16F14_1; Needed for RDR2-independent DNA methylation
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: NERD; Polyclonal Antibody; Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) NERD Polyclonal Antibody; NERD Antibody; Zinc finger CCCH domain-containing protein 19; AtC3H19; Protein Needed for RDR2-independent DNA methylation; NERD At2g16485/At2g16480/At2g16470 F16F14; anti-NERD antibody

• Host: Rabbit
• Reactivity: Arabidopsis thaliana (Mouse-ear cress)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-NERD antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Arabidopsis thaliana NERD protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 240254462
• NCBI GeneID: 816147
• NCBI Accession #: NP_179241.4
• NCBI GenBank Nucleotide #: NM_127202.5
• UniProt Accession #: Q9SIV5; Q8S8E0; Q9SIV4; F4IKD7
• Molecular Weight: 195,051 Da
• NCBI Official Full Name: GW repeat- and PHD finger-containing protein NERD
• NCBI Official Symbol: NERD
• NCBI Official Synonym Symbols: F16F14.1; F16F14_1; Needed for RDR2-independent DNA methylation
• NCBI Protein Information: GW repeat- and PHD finger-containing protein NERD
• UniProt Protein Name: Zinc finger CCCH domain-containing protein 19
• Protein Family: Zinc finger CCCH domain-containing protein
• UniProt Gene Name: NERD
• UniProt Synonym Gene Names: AtC3H19

NCBI Description

Encodes NERD (Needed for RDR2-independent DNA methylation), a plant-specific GW repeat- and PHD finger-containing protein involved in siRNA-dependent DNA methylation.

Uniprot Description

Plays a central role in integrating RNA silencing and chromatin signals in 21 nt siRNA-dependent DNA methylation on cytosine pathway leading to transcriptional gene silencing of specific sequences. Involved in a chromatin-based RNA silencing pathway that encompasses both post-transcriptional gene silencing (PTGS) (e.g. RDR1, RDR6 and AGO2) and transcriptional gene silencing (TGS) (e.g. siRNA-dependent DNA methylation and histone H3) components. Mediates siRNA accumulation at specific chromatin loci. Binds H3K4me0 through its PHD to enforce low levels of H3K4 methylation and gene silencing at a subset of genomic loci.