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Testing Data

anti-Human Thrb Antibody | anti-Thrb antibody

Thrb Antibody

Gene Names
THRB; GRTH; PRTH; THR1; ERBA2; NR1A2; THRB1; THRB2; C-ERBA-2; C-ERBA-BETA
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Protein G-Sepharose affinity purified.
Synonyms
Thrb; Thrb Antibody; Rabbit polyclonal IgG to Thrb; anti-Thrb antibody
Ordering
For Research Use Only!
Reactivity
Human
Purity/Purification
Protein G-Sepharose affinity purified.
Form/Format
Liquid
Sequence Length
461
Applicable Applications for anti-Thrb antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:5000-1:20000
WB: 1:500-1:2000
Immunogen
Full length recombinant protein of human Thrb.
Preservative
0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
Cellular Localization
Nucleus; Cytoplasm
Preparation and Storage
Aliquot and store at-20 degree C. Avoid repeated freeze/thaw cycles.

Testing Data

Testing Data
Related Product Information for anti-Thrb antibody
The Thyroid Hormone Receptor Beta protein is a nuclear hormone receptor for triiodothyronine. It has been shown to mediate the biological activities of, and is one of the several receptors for thyroid hormone. The beta receptor activates expression of several genes known to be important in brain development, implicating it in the well characterised effects of thyroid hormones on development of the fetal and neonatal brain.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
54,449 Da
NCBI Official Full Name
thyroid hormone receptor beta isoform a
NCBI Official Synonym Full Names
thyroid hormone receptor beta
NCBI Official Symbol
THRB
NCBI Official Synonym Symbols
GRTH; PRTH; THR1; ERBA2; NR1A2; THRB1; THRB2; C-ERBA-2; C-ERBA-BETA
NCBI Protein Information
thyroid hormone receptor beta
UniProt Protein Name
Thyroid hormone receptor beta
Protein Family
UniProt Gene Name
THRB
UniProt Synonym Gene Names
ERBA2; NR1A2; THR1

NCBI Description

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.

Research Articles on Thrb

Similar Products

Product Notes

The Thrb thrb (Catalog #AAA859978) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Thrb Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Thrb can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:5000-1:20000 WB: 1:500-1:2000. Researchers should empirically determine the suitability of the Thrb thrb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thrb, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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