Testing Data
(Peptide-+)
Tryptophan Hydroxylase Antibody | anti-TPH antibody
Tryptophan Hydroxylase (Ab-260) Antibody
Gene Names
TPH1; TPRH; TRPH
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
Tryptophan Hydroxylase; Tryptophan Hydroxylase (Ab-260) Antibody; EC 1.14.16.4; TRPH; tryptophan 5-hydroxylase 1; tryptophan 5-monooxygenase 1; anti-TPH antibody
Reactivity
Human, Mouse, Rat
Specificity
Tryptophan Hydroxylase (Ab-260) antibody detects endogenous levels of total Tryptophan Hydroxylase protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
444
Applicable Applications for anti-TPH antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:1000
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human Tryptophan Hydroxylase around the phosphorylation site of serine 260 (H-S-SP-D-P).
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
(Peptide-+)
Testing Data
(Peptide-+)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Tryptophan Hydroxylase (Ab-260) antibody. Western blot analysis of extracts from Jurkat cells, using Tryptophan Hydroxylase (Ab-260) antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Tryptophan Hydroxylase (Ab-260) antibody. Western blot analysis of extracts from Jurkat cells, using Tryptophan Hydroxylase (Ab-260) antibody.)
Immunofluorescence (IF)
(Peptide-+ Immunofluorescence analysis of HeLa cells, using Tryptophan Hydroxylase (Ab-260) antibody.)
Immunofluorescence (IF)
(Peptide-+ Immunofluorescence analysis of HeLa cells, using Tryptophan Hydroxylase (Ab-260) antibody.)
Product Categories/Family for anti-TPH antibody
References
Boulalard S., Nucleic Acids Res. 18:4257-4257(1990). Tipper J.P., Arch. Biochem. Biophys. 315:445-453(1994). The MGC Project Team; Genome Res. 14:2121-2127(2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,394 Da
NCBI Official Full Name
tryptophan 5-hydroxylase 1
NCBI Official Synonym Full Names
tryptophan hydroxylase 1
NCBI Official Symbol
TPH1
NCBI Official Synonym Symbols
TPRH; TRPH
NCBI Protein Information
tryptophan 5-hydroxylase 1
UniProt Protein Name
Tryptophan 5-hydroxylase 1
Protein Family
UniProt Gene Name
TPH1
UniProt Synonym Gene Names
TPH; TPRH; TRPH
NCBI Description
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.[provided by RefSeq, Apr 2009]
Research Articles on TPH
Similar Products
Product Notes
The TPH tph1 (Catalog #AAA858994) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Tryptophan Hydroxylase (Ab-260) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Tryptophan Hydroxylase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:1000. Researchers should empirically determine the suitability of the TPH tph1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tryptophan Hydroxylase, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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