Rabbit anti-Human USP28 Polyclonal Antibody | anti-USP28 antibody

USP28

Cat. Num. AAA8565444

• Reactivity: Human
• Purity: Protein Affinity Purified
• Synonyms: USP28; Polyclonal Antibody; Ubiquitin carboxyl-terminal hydrolase 28; Deubiquitinating enzyme 28; Ubiquitin thioesterase 28; Ubiquitin-specific-processing protease 28; KIAA1515; anti-USP28 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein Affinity Purified
• Form/Format: 1*TBS (pH7.4), 0.5% BSA, 50% Glycerol. 0.05% Sodium Azide.
• Sequence Length: 1077

• Immunogen: Recombinant protein within human USP28 aa 550-700.
• Preparation and Storage: Store at 4 degree C after thawing. Aliquot store at -20 degree C. Avoid repeated freeze/thaw cycles.

NCBI and Uniprot Product Information

• NCBI GI #: 16507200
• NCBI GeneID: 57646
• NCBI Accession #: NP_065937.1
• NCBI GenBank Nucleotide #: NP_065937.1
• UniProt Accession #: Q96RU2
• NCBI Official Full Name: ubiquitin carboxyl-terminal hydrolase 28 isoform a
• NCBI Official Synonym Full Names: ubiquitin specific peptidase 28
• NCBI Official Symbol: USP28
• NCBI Protein Information: ubiquitin carboxyl-terminal hydrolase 28
• UniProt Protein Name: Ubiquitin carboxyl-terminal hydrolase 28
• Protein Family: Ubiquitin carboxyl-terminal hydrolase
• UniProt Gene Name: USP28
• UniProt Synonym Gene Names: KIAA1515
• UniProt Entry Name: UBP28_HUMAN

NCBI Description

The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016]

Uniprot Description

USP28: a peptidase of the C19 family. USP28 and FBXW7 regulate Myc protein stability in response to DNA damage. Two isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin-specific protease; Protease; EC 3.4.19.12

Chromosomal Location of Human Ortholog: 11q23

Cellular Component: nucleoplasm; protein complex; nucleolus; nucleus

Molecular Function: protein binding; cysteine-type endopeptidase activity; ubiquitin-specific protease activity

Biological Process: cell proliferation; proteasomal ubiquitin-dependent protein catabolic process; protein deubiquitination; DNA damage checkpoint; response to ionizing radiation; DNA repair; response to DNA damage stimulus; DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis