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Rabbit PLCD1 Polyclonal Antibody | anti-PLCD1 antibody

PLCD1

Gene Names
PLCD1; NDNC3; PLC-III
Reactivity
Human
Predicted: Rat, Mouse
Applications
ELISA, Western Blot
Purity
Purified By Antigen Affinity Column
Synonyms
PLCD1; Polyclonal Antibody; Purified Rabbit Anti Human PLCD1 Polyclonal antibody; NDNC3; PLC-III; anti-PLCD1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
2674
Applicable Applications for anti-PLCD1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20000-80000
WB: 1:200-1,000
Immunogen
Recombinant fragment corresponding to 534-689aa of human PLCD1.
Cellular Localization
Cytosol
Related Product Information for anti-PLCD1 antibody
Homo sapiens phospholipase C, delta 1, mRNA
References
Mu H, Wang N, Zhao L. Methylation of PLCD1 and adenovirus-mediated PLCD1 overexpression elicits a gene therapy effect on human breast cancer. Exp Cell Res. 332(2):179-89. (2015)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
86KD
NCBI Official Full Name
Homo sapiens phospholipase C, delta 1, mRNA
NCBI Official Synonym Full Names
phospholipase C delta 1
NCBI Official Symbol
PLCD1
NCBI Official Synonym Symbols
NDNC3; PLC-III
NCBI Protein Information
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1

NCBI Description

This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Research Articles on PLCD1

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Product Notes

The PLCD1 (Catalog #AAA8563773) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLCD1 reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PLCD1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20000-80000 WB: 1:200-1,000. Researchers should empirically determine the suitability of the PLCD1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLCD1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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