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Rabbit SYT12 Polyclonal Antibody | anti-SYT12 antibody

SYT12

Gene Names
SYT12; SYT11; sytXII
Reactivity
Human
Predicted: Rat, Mouse
Applications
ELISA, Western Blot
Purity
Purified By Antigen Affinity Column
Synonyms
SYT12; Polyclonal Antibody; SYT11; sytXII; anti-SYT12 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted: Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified By Antigen Affinity Column
Form/Format
Already dissolved in sterile H2O with 1% BSA and 0.02% NaN3 and 50% Glycerol.
Sequence Length
3520
Applicable Applications for anti-SYT12 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:20,000-80,000
WB: 1:200-1,000
Immunogen
Recombinant fragment corresponding to 234-405aa of human SYT12.
Cellular Localization
Cell Junction, Cytoplasmic Vesicle, Membrane, Synapse
Related Product Information for anti-SYT12 antibody
Synaptotagmin-12
References
Psychiatric GWAS Consortium Bipolar Disorder Working Group. Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat. Genet. 43(10):977-983 (2011)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
47KD
NCBI Official Full Name
Homo sapiens synaptotagmin XII, mRNA
NCBI Official Synonym Full Names
synaptotagmin 12
NCBI Official Symbol
SYT12
NCBI Official Synonym Symbols
SYT11; sytXII
NCBI Protein Information
synaptotagmin-12
Protein Family

NCBI Description

This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.[provided by RefSeq, Apr 2010]

Research Articles on SYT12

Similar Products

Product Notes

The SYT12 (Catalog #AAA8561843) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYT12 reacts with Human Predicted: Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SYT12 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:20,000-80,000 WB: 1:200-1,000. Researchers should empirically determine the suitability of the SYT12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYT12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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