Rabbit anti-Human P2RX3 Polyclonal Antibody | anti-P2RX3 antibody
P2RX3 Rabbit pAb
IHC: 25-100
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the P2X purinergic receptor (purinoceptor) gene family which includes seven members (P2RX1 - P2RX7). P2X purinoceptors are a family of cation-permeable, ligand-gated ion channels that open in response to the binding of extracellular adenosine 5'-triphosphate (ATP). The encoded protein is a subunit of the trimeric P2X3 receptor ion channel which is expressed by sensory or autonomic neurons. A deficiency of the orthologous protein in mice is associated with reduced pain-related behavior and urinary bladder hyporeflexia. [provided by RefSeq, Aug 2017]
Uniprot Description
P2X3: Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.
Protein type: Membrane protein, multi-pass; Channel, ligand-gated; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11q12
Cellular Component: Golgi apparatus; cell soma; rough endoplasmic reticulum; integral to plasma membrane; dendritic spine; terminal button; integral to nuclear inner membrane; receptor complex; lipid raft
Molecular Function: ATP binding; purinergic nucleotide receptor activity; ATP-gated cation channel activity
Biological Process: urinary bladder smooth muscle contraction; peristalsis; sensory perception of taste; generation of action potential; regulation of synaptic plasticity; positive regulation of calcium-mediated signaling; signal transduction; response to ATP; response to carbohydrate stimulus; behavioral response to pain; transport; response to heat; response to mechanical stimulus; response to hypoxia; neuromuscular synaptic transmission; response to cold; protein homooligomerization
Research Articles on P2RX3
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Product Notes
The P2RX3 p2rx3 (Catalog #AAA8559955) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The P2RX3 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's P2RX3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 200-1000 IHC: 25-100. Researchers should empirically determine the suitability of the P2RX3 p2rx3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "P2RX3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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