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Immunofluorescence (IF) (Peptide-+ Immunofluorescence analysis of HeLa cells, using TNF14 antibody.)

anti-Human TNF14 Antibody | anti-TNF14 antibody

TNF14 Antibody

Gene Names
TNFSF14; LTg; CD258; HVEML; LIGHT
Reactivity
Human
Applications
Immunofluorescence, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
TNF14; TNF14 Antibody; Tumor necrosis factor ligand superfamily member 14; Herpesvirus entry mediator-ligand; HVEM-L; CD258 antigen; membrane form; soluble form; TNFSF14; HVEML; LIGHT; UNQ391/PRO726; anti-TNF14 antibody
Ordering
For Research Use Only!
Reactivity
Human
Specificity
TNF14 antibody detects endogenous levels of total TNF14 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
240
Applicable Applications for anti-TNF14 antibody
Immunofluorescence (IF), ELISA (EIA)
Application Notes
IF: 1:100-1:500
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human TNF14.
Preparation and Storage
Store at-20 degree C for 1 year.

Immunofluorescence (IF)

(Peptide-+ Immunofluorescence analysis of HeLa cells, using TNF14 antibody.)

Immunofluorescence (IF) (Peptide-+ Immunofluorescence analysis of HeLa cells, using TNF14 antibody.)
References
Mauri D.N., Immunity 8:21-30(1998). Harrop J.A., J. Biol. Chem. 273:27548-27556(1998). Granger S.W., J. Immunol. 167:5122-5128(2001).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
22,395 Da
NCBI Official Full Name
tumor necrosis factor ligand superfamily member 14 isoform 1
NCBI Official Synonym Full Names
TNF superfamily member 14
NCBI Official Symbol
TNFSF14
NCBI Official Synonym Symbols
LTg; CD258; HVEML; LIGHT
NCBI Protein Information
tumor necrosis factor ligand superfamily member 14
UniProt Protein Name
Tumor necrosis factor ligand superfamily member 14
UniProt Gene Name
TNFSF14
UniProt Synonym Gene Names
HVEML; LIGHT; HVEM-L; Herpesvirus entry mediator ligand

NCBI Description

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Uniprot Description

Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.

Research Articles on TNF14

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Product Notes

The TNF14 tnfsf14 (Catalog #AAA855831) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The TNF14 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TNF14 can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF), ELISA (EIA). IF: 1:100-1:500 ELISA: 1:20000. Researchers should empirically determine the suitability of the TNF14 tnfsf14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNF14, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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