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Rabbit anti-Human SKIV2L2 Polyclonal Antibody | anti-SKIV2L2 antibody

SKIV2L2 (Center) Rabbit pAb

Gene Names
MTREX; Dob1; Mtr4; SKIV2L2; fSAP118; KIAA0052
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Affinity Purified
Synonyms
SKIV2L2; Polyclonal Antibody; SKIV2L2 (Center) Rabbit pAb; Superkiller viralicidic activity 2-like 2; ATP-dependent RNA helicase SKIV2L2; TRAMP-like complex helicase; KIAA0052; Mtr4; anti-SKIV2L2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Clone Number
RB22430
Purity/Purification
Affinity Purified
Form/Format
Supplied in PBS with 0.09% (W/V) Sodium Azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Length
1042
Applicable Applications for anti-SKIV2L2 antibody
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
WB: 1:1000
IHC: 1:50-100
FC/FACS: 1:10-50
Immunogen
This SKIV2L2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-263 amino acids from the central region of human SKIV2L2.
Cellular Localization
Nucleus, Spliceosome

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
Exosome RNA helicase MTR4
NCBI Official Synonym Full Names
Mtr4 exosome RNA helicase
NCBI Official Symbol
MTREX
NCBI Official Synonym Symbols
Dob1; Mtr4; SKIV2L2; fSAP118; KIAA0052
NCBI Protein Information
exosome RNA helicase MTR4
UniProt Protein Name
Superkiller viralicidic activity 2-like 2
UniProt Gene Name
SKIV2L2
UniProt Synonym Gene Names
KIAA0052; Mtr4
UniProt Entry Name
SK2L2_HUMAN

Uniprot Description

SKIV2L2: May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Belongs to the helicase family. SKI2 subfamily.

Protein type: Spliceosome; EC 3.6.4.13; Nucleolus; DNA-binding; Helicase

Chromosomal Location of Human Ortholog: 5q11.2

Cellular Component: nucleoplasm; nucleolus; exosome (RNase complex); nucleus

Molecular Function: protein binding; helicase activity; ATP binding

Biological Process: nuclear mRNA splicing, via spliceosome; maturation of 5.8S rRNA

Research Articles on SKIV2L2

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Product Notes

The SKIV2L2 skiv2l2 (Catalog #AAA8555342) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SKIV2L2 (Center) Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SKIV2L2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB: 1:1000 IHC: 1:50-100 FC/FACS: 1:10-50. Researchers should empirically determine the suitability of the SKIV2L2 skiv2l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SKIV2L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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