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Rabbit anti-Human GRAF Polyclonal Antibody | anti-GRAF antibody

GRAF (OPHN1L) (Center) Rabbit pAb

Gene Names
ARHGAP26; GRAF; GRAF1; OPHN1L; OPHN1L1
Reactivity
Human
Applications
Western Blot
Purity
Affinity Purified
Synonyms
GRAF; Polyclonal Antibody; GRAF (OPHN1L) (Center) Rabbit pAb; Rho GTPase-activating protein 26; GTPase regulator associated with focal adhesion kinase; Oligophrenin-1-like protein; Rho-type GTPase-activating protein 26; ARHGAP26; KIAA0621; OPHN1L; anti-GRAF antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Ig
Clone Number
RB3722
Purity/Purification
Affinity Purified
Form/Format
Supplied in PBS with 0.09% (W/V) Sodium Azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Sequence Length
759
Applicable Applications for anti-GRAF antibody
Western Blot (WB)
Application Notes
WB: 1:1000
Immunogen
This GRAF (OPHN1L) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-267 amino acids from the central region of human GRAF (OPHN1L).
Cellular Localization
Cell Junction, Cytoplasm, Cytoskeleton

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
rho GTPase-activating protein 26 isoform b
NCBI Official Synonym Full Names
Rho GTPase activating protein 26
NCBI Official Symbol
ARHGAP26
NCBI Official Synonym Symbols
GRAF; GRAF1; OPHN1L; OPHN1L1
NCBI Protein Information
rho GTPase-activating protein 26
UniProt Protein Name
Rho GTPase-activating protein 26
UniProt Gene Name
ARHGAP26
UniProt Synonym Gene Names
GRAF; KIAA0621; OPHN1L
UniProt Entry Name
RHG26_HUMAN

NCBI Description

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2017]

Research Articles on GRAF

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Product Notes

The GRAF arhgap26 (Catalog #AAA8555208) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The GRAF (OPHN1L) (Center) Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's GRAF can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000. Researchers should empirically determine the suitability of the GRAF arhgap26 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GRAF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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