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Western Blot (WB) ( Western blot analysis of extracts of rat thymus, using T2R38 antibody (MBS8532047) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit. Exposure time: 90s.)

Rabbit T2R38 Polyclonal Antibody | anti-T2R38 antibody

Taste receptor type 2 member 38 (T2R38) (PTC bitter taste receptor) (Taste receptor type 2 member 61)

Gene Names
TAS2R38; PTC; T2R38; T2R61
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
T2R38; Polyclonal Antibody; Taste receptor type 2 member 38 (T2R38) (PTC bitter taste receptor) (Taste receptor type 2 member 61); T2R61; TAS2R38; PTC; anti-T2R38 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
T2R38 Polyclonal Antibody detects endogenous levels of protein.
Purity/Purification
affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
333
Applicable Applications for anti-T2R38 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-2000
ELISA: 1:5000-20000
Immunogen
Synthesized peptide derived from human protein . at AA range: 180-260
Preparation and Storage
-20°C/1 year

Western Blot (WB)

( Western blot analysis of extracts of rat thymus, using T2R38 antibody (MBS8532047) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit. Exposure time: 90s.)

Western Blot (WB) ( Western blot analysis of extracts of rat thymus, using T2R38 antibody (MBS8532047) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit. Exposure time: 90s.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed band: 36 kDa
NCBI Official Full Name
taste receptor type 2 member 38
NCBI Official Synonym Full Names
taste 2 receptor member 38
NCBI Official Symbol
TAS2R38
NCBI Official Synonym Symbols
PTC; T2R38; T2R61
NCBI Protein Information
taste receptor type 2 member 38
UniProt Protein Name
Taste receptor type 2 member 38
UniProt Gene Name
TAS2R38
UniProt Synonym Gene Names
PTC; T2R38; T2R61

NCBI Description

This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant). [provided by RefSeq, Oct 2009]

Uniprot Description

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 ().

Research Articles on T2R38

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Product Notes

The T2R38 tas2r38 (Catalog #AAA8532047) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Taste receptor type 2 member 38 (T2R38) (PTC bitter taste receptor) (Taste receptor type 2 member 61) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's T2R38 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-2000 ELISA: 1:5000-20000. Researchers should empirically determine the suitability of the T2R38 tas2r38 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "T2R38, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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