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Testing Data (Peptide-+)

C1QC Antibody | anti-C1QC antibody

C1QC Antibody

Gene Names
C1QC; C1QG; C1Q-C
Reactivity
Human (Identities= 100%, Positives= 100%)
Mouse (Identities= 85%, Positives= 85%)
Rat (Identities= 92%, Positives= 92%)
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
C1QC; C1QC Antibody; Complement C1q subcomponent subunit C; anti-C1QC antibody
Ordering
For Research Use Only!
Reactivity
Human (Identities= 100%, Positives= 100%)
Mouse (Identities= 85%, Positives= 85%)
Rat (Identities= 92%, Positives= 92%)
Specificity
C1QC antibody detects endogenous levels of total C1QC protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
245
Applicable Applications for anti-C1QC antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human C1QC.
Preparation and Storage
Store at-20 degree C for 1 year.

Testing Data

(Peptide-+)

Testing Data (Peptide-+)

Immunohistochemistry (IHC)

(Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using C1QC antibody. Western blot analysis of extracts from rat lung cells, using C1QC antibody.)

Immunohistochemistry (IHC) (Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using C1QC antibody. Western blot analysis of extracts from rat lung cells, using C1QC antibody.)
References
Sellar G.C., Biochem. J. 274:481-490(1991). Dai F.Y., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. Ota T., Nat. Genet. 36:40-45(2004).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
714
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
complement C1q subcomponent subunit C isoform 1
NCBI Official Synonym Full Names
complement C1q C chain
NCBI Official Symbol
C1QC
NCBI Official Synonym Symbols
C1QG; C1Q-C
NCBI Protein Information
complement C1q subcomponent subunit C
UniProt Protein Name
Complement C1q subcomponent subunit C
UniProt Gene Name
C1QC
UniProt Synonym Gene Names
C1QG

NCBI Description

This gene encodes the C-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. [provided by RefSeq, Dec 2016]

Uniprot Description

C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca2+-dependent C1r2C1s2 proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

Research Articles on C1QC

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Product Notes

The C1QC c1qc (Catalog #AAA853200) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The C1QC Antibody reacts with Human (Identities= 100%, Positives= 100%) Mouse (Identities= 85%, Positives= 85%) Rat (Identities= 92%, Positives= 92%) and may cross-react with other species as described in the data sheet. AAA Biotech's C1QC can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000. Researchers should empirically determine the suitability of the C1QC c1qc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "C1QC, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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