SP-A Polyclonal Antibody | anti-SP-A antibody

SP-A Polyclonal Antibody

Cat. Num. AAA8526172

• Gene Names: SFTPA2; PSAP; PSPA; SP-A; SPA2; PSP-A; SFTP1; SP-2A; SPAII; COLEC5; SFTPA2B
• Synonyms: SP-A; Polyclonal Antibody; SP-A Polyclonal Antibody; anti-SP-A antibody

• Clonality: Polyclonal
• Sequence Length: 248

NCBI and Uniprot Product Information

• NCBI GI #: 148886696
• NCBI GeneID: 729238
• NCBI Accession #: NP_001092138.1
• NCBI GenBank Nucleotide #: NM_001098668.3
• UniProt Accession #: Q8IWL1; P07714; Q14DV3; Q5RIR8; A4QPA7; B2RXI6; B2RXK9; C9J9I7; E3VLC6; E3VLC7; E3VLC8; E3VLC9
• Molecular Weight: 26,182 Da
• NCBI Official Full Name: pulmonary surfactant-associated protein A2 isoform 1
• NCBI Official Synonym Full Names: surfactant protein A2
• NCBI Official Symbol: SFTPA2
• NCBI Official Synonym Symbols: PSAP; PSPA; SP-A; SPA2; PSP-A; SFTP1; SP-2A; SPAII; COLEC5; SFTPA2B
• NCBI Protein Information: pulmonary surfactant-associated protein A2
• UniProt Protein Name: Pulmonary surfactant-associated protein A2
• UniProt Gene Name: SFTPA2
• UniProt Synonym Gene Names: COLEC5; PSAP; SFTP1; SFTPA; SFTPA2B; PSP-A; PSPA; SP-A; SP-A2

NCBI Description

This gene is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication. [provided by RefSeq, Sep 2009]

Uniprot Description

In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.