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Testing Data

Rabbit BCL2L2 Polyclonal Antibody | anti-BCL2L2 antibody

BCL2L2 Antibody

Gene Names
BCL2L2; BCLW; BCL-W; PPP1R51; BCL2-L-2
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Synonyms
BCL2L2; Polyclonal Antibody; BCL2L2 Antibody; anti-BCL2L2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Form/Format
Purified by peptide affinity column containing 2% BSA and 0.02% NaN3
Sequence Length
193
Applicable Applications for anti-BCL2L2 antibody
Peptide ELISA (EIA), Western Blot (WB)
Application Notes
Peptide ELISA: 1:1,000-1:10,000
WB: 1:200-1,000
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.

Testing Data

Testing Data
Related Product Information for anti-BCL2L2 antibody
Rabbit polyclonal BCL2L2 (1) antibody was raised against a 14 amino acid peptide from N terminal residues of human BCL2L2.
References
(1) Kim, D.H., Xu, W., Ma, C., Liu, X., et al. Genetic variants in the candidate genes of the apoptosis pathway and susceptibility to chronic myeloid leukemia. Blood 113 (11), 2517-2525 (2009).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
599
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37,171 Da
NCBI Official Full Name
bcl-2-like protein 2
NCBI Official Synonym Full Names
BCL2 like 2
NCBI Official Symbol
BCL2L2
NCBI Official Synonym Symbols
BCLW; BCL-W; PPP1R51; BCL2-L-2
NCBI Protein Information
bcl-2-like protein 2
UniProt Protein Name
Bcl-2-like protein 2
Protein Family
UniProt Gene Name
BCL2L2
UniProt Synonym Gene Names
BCLW; KIAA0271; Bcl2-L-2

NCBI Description

This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]

Uniprot Description

Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.

Research Articles on BCL2L2

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Product Notes

The BCL2L2 bcl2l2 (Catalog #AAA851564) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BCL2L2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BCL2L2 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: 1:1,000-1:10,000 WB: 1:200-1,000. Researchers should empirically determine the suitability of the BCL2L2 bcl2l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCL2L2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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