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Western Blot (WB) (Figure 1. Western blot analysis using SARS-mpm mouse mAb against SARS-mpm recombinant protein.)

Mouse SARS-M Antibody | anti-SARS-M antibody

SARS-M Antibody

Reactivity
Human coronavirus
Applications
Western Blot, ELISA
Synonyms
SARS-M; SARS-M Antibody; anti-SARS-M antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
Human coronavirus
Isotype
IgG1
Clone Number
2H2C4
Form/Format
Purified antibody in PBS containing 0.03% sodium azide.
Sequence Length
71
Applicable Applications for anti-SARS-M antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB: 1:500-1:2000
ELISA: 1:10000
Immunogen
Purified recombinant fragment of SARS-m protein expressed in E. Coli.
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Preparation and Storage
Store at 4 degree C, for long term storage, store at-20 degree C

Western Blot (WB)

(Figure 1. Western blot analysis using SARS-mpm mouse mAb against SARS-mpm recombinant protein.)

Western Blot (WB) (Figure 1. Western blot analysis using SARS-mpm mouse mAb against SARS-mpm recombinant protein.)
Related Product Information for anti-SARS-M antibody
SARS (severe acute respiratory syndrome) is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness, such as the common cold, in humans. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The complete sequence of the SARS virus release the coronavirus contains 25 open reading frames. SARS-m is a membrane (M) protein which plays a the key player in virion assembly. One of its functions is to mediate the incorporation of the spikes into the viral envelope.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
58,605 Da
NCBI Official Full Name
SARS protein, partial
NCBI Official Synonym Full Names
seryl-tRNA synthetase
NCBI Official Symbol
SARS
NCBI Protein Information
serine--tRNA ligase, cytoplasmic
UniProt Protein Name
Serine--tRNA ligase, cytoplasmic
UniProt Gene Name
SARS
UniProt Synonym Gene Names
SERS; SerRS

Uniprot Description

Catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction: serine is first activated by ATP to form Ser-AMP and then transferred to the acceptor end of tRNA(Ser). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec). In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC. Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at 'Lys-16' (H4K16). Thereby, inhibits the production of VEGFA and sprouting angiogenesis mediated by VEGFA.

Research Articles on SARS-M

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Product Notes

The SARS-M sars (Catalog #AAA850682) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The SARS-M Antibody reacts with Human coronavirus and may cross-react with other species as described in the data sheet. AAA Biotech's SARS-M can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:500-1:2000 ELISA: 1:10000. Researchers should empirically determine the suitability of the SARS-M sars for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SARS-M, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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