Testing Data
anti-Human, Mouse LDH-A Antibody | anti-LDH-A antibody
LDH-A Antibody
Gene Names
LDHA; LDHM; GSD11; PIG19; HEL-S-133P
Reactivity
Human, Mouse
Applications
Western Blot
Synonyms
LDH-A; LDH-A Antibody; anti-LDH-A antibody
Reactivity
Human, Mouse
Clone Number
20-179
Specificity
This antibody is produced by immunizing mouse with a synthetic peptide (KLH-coupled) corresponding to near N-terminal residues of LDH-A.
Form/Format
In 1*TBS (pH7.4), 0.5%BSA, 25%Glycerol.
Sequence Length
274
Applicable Applications for anti-LDH-A antibody
Western Blot (WB)
Application Notes
WB: 1:500
Preservative
0.05% Sodium Azide.
Cellular Localization
Cytoplasm
Positive Control
A549
Preparation and Storage
Store at +4 degree C after thawing. Aliquot store at-20 degree C or-80 degree C. Avoid repeated freeze/thaw cycles.
Testing Data
Testing Data
Related Product Information for anti-LDH-A antibody
Lactate dehydrogenase (LDH) is an enzyme present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. In medicine, LDH is often used as a marker of tissue breakdown as LDH is abundant in red blood cells and can function as a marker for hemolysis. In mammals, three types of LDH subunits (35 kDa) are encoded by the genes Ldh-A, Ldh-B, and Ldh-C. Lactate dehydrogenase B (LDH-B, heart subunit, LDH-H) is involved in the conversion of L-lactate and NAD to pryruvate and NADH and it is predominantly localized in the heart tissue. Similar to other LDH subunit, LDH-B is considered to be an important marker for germ cell tumor.
References
1. Kopperschlager G et al. J Chromatogr B Biomed Appl. 684(1-2):25-49, 1996. 2. Li X et al. Biochem Biophys Res Commun. 320(3):625-634, 2004. 3. Kanno T et al. Clin Chim Acta. 173(1):89-98, 1998.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
~35kDa
NCBI Official Full Name
L-lactate dehydrogenase A chain isoform 2
NCBI Official Synonym Full Names
lactate dehydrogenase A
NCBI Official Symbol
LDHA
NCBI Official Synonym Symbols
LDHM; GSD11; PIG19; HEL-S-133P
NCBI Protein Information
L-lactate dehydrogenase A chain
UniProt Protein Name
L-lactate dehydrogenase A chain
UniProt Gene Name
LDHA
UniProt Synonym Gene Names
LDH-A; LDH-M
NCBI Description
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2008]
Research Articles on LDH-A
Similar Products
Product Notes
The LDH-A ldha (Catalog #AAA850658) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The LDH-An Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's LDH-A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500. Researchers should empirically determine the suitability of the LDH-A ldha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LDH-A, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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