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Testing Data

Mouse HA Monoclonal Antibody | anti-HA antibody

Anti-HA (H5N1) Monoclonal Antibody

Applications
Flow Cytometry, Functional Assay, Immunofluorescence, Western Blot
Synonyms
HA; Monoclonal Antibody; Anti-HA (H5N1) Monoclonal Antibody; anti-HA antibody
Ordering
For Research Use Only!
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
9F4
Form/Format
Colorless liquid
Sequence Length
567
Applicable Applications for anti-HA antibody
Flow Cytometry (FC/FACS); Immunofluorescence (IF); Western Blot (WB)
Immunogen
HA full length that was expressed and purified from insect cells
Preparation and Storage
Store at -20 degree C for 12 months.
The antibody solution should be gently mixed before use.

Testing Data

Testing Data
Related Product Information for anti-HA antibody
Monoclonal antibody to detect HA (H5N1).
Binds to sialic acid-containing receptors on the cell surface; bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2; releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore. The recombinant HA protein of a clade H5N1 virus was used to generate monoclonal antibodies for viral neutralization assays. The HA full-length protein was expressed in insect cells infected with baculovirus carrying the HA gene to ensure that it underwent glycosylation.

NCBI and Uniprot Product Information

NCBI GeneID
UniProt Accession #
Molecular Weight
64,077 Da
UniProt Protein Name
Hemagglutinin
Protein Family
UniProt Gene Name
HA

Uniprot Description

Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.

Similar Products

Product Notes

The HA ha (Catalog #AAA846118) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's HA can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS); Immunofluorescence (IF); Western Blot (WB). Researchers should empirically determine the suitability of the HA ha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HA, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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