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Rabbit PI4KB Polyclonal Antibody | anti-PI4KB antibody

PI4KB antibody

Gene Names
PI4KB; NPIK; PI4K92; PIK4CB; PI4KBETA; PI4K-BETA; PI4KIIIBETA
Applications
ELISA, Western Blot
Purity
PI4KB antibody was purified by Antigen Affinity chromatography
Synonyms
PI4KB; Polyclonal Antibody; PI4KB antibody; Polyclonal PI4KB; Anti-PI4KB; Phosphatidylinositol 4 Kinase Catalytic Beta; Pi4Kb; Pi4K Beta; Pi4KIIIbeta; Pi4Kbeta; Pik4Cb; Pi4K92; anti-PI4KB antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
PI4KB antibody was purified by Antigen Affinity chromatography
Form/Format
Supplied in PBS buffer with 0.02% Sodium Azide and 50% Glycerol, pH 7.3
Sequence Length
484
Applicable Applications for anti-PI4KB antibody
ELISA (EIA), Western Blot (WB)
Biological Significance
PI4KB phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol-1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
PI4KB antibody was raised in Rabbit using Human PI4KB as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage and -20 degree C for long term storage. Avoid repeat freeze/thaw cycles
Related Product Information for anti-PI4KB antibody
Rabbit polyclonal PI4KB antibody
Product Categories/Family for anti-PI4KB antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54,976 Da
NCBI Official Full Name
phosphatidylinositol 4-kinase beta isoform 3
NCBI Official Synonym Full Names
phosphatidylinositol 4-kinase, catalytic, beta
NCBI Official Symbol
PI4KB
NCBI Official Synonym Symbols
NPIK; PI4K92; PIK4CB; PI4KBETA; PI4K-BETA; PI4KIIIBETA
NCBI Protein Information
phosphatidylinositol 4-kinase beta
UniProt Protein Name
Phosphatidylinositol 4-kinase beta
UniProt Gene Name
PI4KB
UniProt Synonym Gene Names
PIK4CB; PI4K-beta; PI4Kbeta; PtdIns 4-kinase beta
UniProt Entry Name
PI4KB_HUMAN

Uniprot Description

PIK4CB: a member of the PI3/PI4 kinase family. Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate. Found in the outer membrane of mitochondria and membranes of the rough endoplasmic reticulum. Recruited to the Golgi complex by the small GTPase ARF to stimulate the synthesis of phosphatidylinositol 4,5-biphosphate (PIP2) on the Golgi complex. May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Three splice-variant isoforms have been described.

Protein type: Carbohydrate Metabolism - inositol phosphate; EC 2.7.1.67; Motility/polarity/chemotaxis; Kinase, lipid

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: Golgi membrane; mitochondrial outer membrane; perinuclear region of cytoplasm; cytoplasm; plasma membrane; rough endoplasmic reticulum membrane; cytosol; endosome

Molecular Function: 1-phosphatidylinositol 4-kinase activity; protein binding; ATP binding

Biological Process: receptor-mediated endocytosis; phosphoinositide-mediated signaling; phosphoinositide phosphorylation; phospholipid metabolic process; phosphatidylinositol biosynthetic process; signal transduction

Research Articles on PI4KB

Similar Products

Product Notes

The PI4KB pi4kb (Catalog #AAA838900) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PI4KB can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the PI4KB pi4kb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PI4KB, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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