Western Blot (WB)
()
Rabbit PP2A alpha Polyclonal Antibody | anti-PP2A alpha antibody
PP2A alpha antibody
Gene Names
ppp2r2a; pp2a
Applications
Western Blot
Synonyms
PP2A alpha; Polyclonal Antibody; PP2A alpha antibody; Polyclonal PP2A alpha; Anti-PP2A alpha; PPP2CA; protein phosphatase 2; catalytic subunit; alpha isozyme; BOS_8121; PP2A; Pp2a1; PP2A-alpha; PP2Ac; PP2CA; PP2Calpha; protein phosphatase-2A-alpha; protein phosphatase 2A alpha subunit; protein phosphatase 2a; alpha isoform; protein phosphatase 2A catalytic subunit; protein phosphatase 2A; beta isoform; protein phosphatase 2 (formerly 2A); R75353; RCJMB04_3c21; replication protein C; RP23-46N3.2; rp-c; serine/threonine protein phosphatase 2A; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; type 2A protein phosphatase catalytic subunit; anti-PP2A alpha antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Form/Format
Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
Sequence Length
444
Applicable Applications for anti-PP2A alpha antibody
Western Blot (WB)
Application Notes
WB: 1:1000-2000
Biological Significance
Protein Phosphatase 2A (PP2A) is one of the major Ser/Thr phosphatases implicated in the regulation of many cellular processes including regulation of different signal transduction pathways, cell cycle progression, DNA replication, gene transcription and protein translation. The core structure comprises a 36 kDa catalytic subunit (PP2AC) and a 65 kDa regulatory subunit (PR65 or A subunit). Each PP2A subunit has at least two isoforms and the catalytic subunit, present in the alpha and beta isoforms, share 97% homology. The differential association of all these subunits gives rise to an extensive subset of oligomeric holoenzymes. It is widely thought that PP2A exercises regulatory flexibility and differential substrate specificity through the specific association of the core dimer (PP2AD) with one of the three regulatory B subunits. Moreover, PP2A interacts with a still growing number of cellular and viral proteins and is regulated by posttranslational modifications.
Cross-Reactivity
Human, Mouse, Rat
Immunogen
PP2A alpha antibody was raised in Rabbit using a synthetic target peptide as the immunogen
Preparation and Storage
Aliquot and store for 1 year at -20 degree C, avoid freeze/thaw cycles
Western Blot (WB)
()
Western Blot (WB)
()
Related Product Information for anti-PP2A alpha antibody
Rabbit polyclonal PP2A alpha antibody
Product Categories/Family for anti-PP2A alpha antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
protein phosphatase 2, regulatory subunit B, alpha
NCBI Official Synonym Full Names
protein phosphatase 2, regulatory subunit B, alpha
NCBI Official Symbol
ppp2r2a
NCBI Official Synonym Symbols
pp2a
NCBI Protein Information
protein phosphatase 2, regulatory subunit B, alpha
Research Articles on PP2A alpha
Similar Products
Product Notes
The PP2A alpha (Catalog #AAA837235) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PP2A alpha can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:1000-2000. Researchers should empirically determine the suitability of the PP2A alpha for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PP2A alpha, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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