Mouse alpha Adaptin Monoclonal Antibody | anti-alpha-ADR antibody
alpha Adaptin antibody
Gene Names
alpha-ADR; alpha-adaptin; alpha-ADR; MDJ22.19; MDJ22_19
Applications
Western Blot
Synonyms
alpha Adaptin; Monoclonal Antibody; alpha Adaptin antibody; Monoclonal alpha Adaptin; Anti-alpha Adaptin; DKFZp667D2317; Alpha and gamma-adaptin binding protein; FLJ11506; p34; Adaptor related protein complex alpha 1 subunit; anti-alpha-ADR antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
Ada-1
Form/Format
Supplied in lyophilized form
Sequence Length
1012
Applicable Applications for anti-alpha-ADR antibody
Western Blot (WB)
Application Notes
Optimal conditions to be determined by the end user
Biological Significance
The alpha adaptins are exclusively found in the endocytic coated vesicles. Huntingtin-interacting protein 1 (HIP1) is enriched in membrane-containing cell fractions and has been implicated in vesicle trafficking. Waelter et al. (2001) identified 3 HIP1-associated proteins, clathrin heavy chain (CLTC)and alpha-adaptin A and C. Coat proteins of approximately 100-kD (adaptins) are components of the adaptor complexes which link clathrin to receptors in coated vesicles. The alpha-adaptins separate into two bands on SDS gels.
Immunogen
alpha Adaptin antibody was raised in mouse using AP-2 adaptor polypeptides from bovine brain as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage. For long term storage aliquot and store at -20 degree C, avoid repeated freeze/thaw cycles.
Related Product Information for anti-alpha-ADR antibody
Mouse monoclonal alpha Adaptin antibody
Product Categories/Family for anti-alpha-ADR antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
104,019 Da
NCBI Official Full Name
alpha-adaptin
NCBI Official Symbol
alpha-ADR
NCBI Official Synonym Symbols
alpha-adaptin; alpha-ADR; MDJ22.19; MDJ22_19
NCBI Protein Information
alpha-adaptin
UniProt Protein Name
AP-2 complex subunit alpha-1
UniProt Gene Name
ALPHA-ADR
UniProt Synonym Gene Names
At-a-Ad; At-alpha-Ad
UniProt Entry Name
AP2A1_ARATH
Uniprot Description
Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The complex binds polyphosphoinositides ().
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Product Notes
The alpha-ADR alpha-adr (Catalog #AAA834445) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's alpha Adaptin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Optimal conditions to be determined by the end user. Researchers should empirically determine the suitability of the alpha-ADR alpha-adr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "alpha Adaptin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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