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Western Blot (WB) (Western blot analysis of IQGAP2 expression in Jurkat (A), mouse liver (B) whole cell lysates.)

Rabbit anti-Human, Mouse IQGAP2 Polyclonal Antibody | anti-IQGAP2 antibody

Anti-IQGAP2 Antibody

Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Immunogen Affinity Chromatography
Synonyms
IQGAP2; Polyclonal Antibody; Anti-IQGAP2 Antibody; Ras GTPase-activating-like protein IQGAP2; anti-IQGAP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of IQGAP2 protein.
Purity/Purification
Purified by Immunogen Affinity Chromatography
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Applicable Applications for anti-IQGAP2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Recombinant fusion protein of human IQGAP2. The exact sequence is proprietary.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of IQGAP2 expression in Jurkat (A), mouse liver (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of IQGAP2 expression in Jurkat (A), mouse liver (B) whole cell lysates.)
Related Product Information for anti-IQGAP2 antibody
Rabbit polyclonal antibody to IQGAP2

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
122,806 Da
NCBI Official Full Name
ras GTPase-activating-like protein IQGAP2 isoform 1
NCBI Official Synonym Full Names
IQ motif containing GTPase activating protein 2
NCBI Official Symbol
IQGAP2
NCBI Protein Information
ras GTPase-activating-like protein IQGAP2
UniProt Protein Name
Ras GTPase-activating-like protein IQGAP2
UniProt Gene Name
IQGAP2
UniProt Entry Name
IQGA2_HUMAN

NCBI Description

This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility. [provided by RefSeq, Jul 2008]

Uniprot Description

IQGAP2: Binds to activated CDC42 and RAC1 but does not seem to stimulate their GTPase activity. Associates with calmodulin. Isoform 2 expression is enhanced in testis. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein regulator, misc.; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 5q13.3

Cellular Component: filamentous actin; microtubule; microvillus; cell surface; lamellipodium; cytoplasm; actin cytoskeleton; filopodium

Molecular Function: calmodulin binding; actin filament binding; phosphatidylinositol-3,4,5-triphosphate binding; Rho GTPase binding; Rac GTPase binding; actin binding; GTPase inhibitor activity

Biological Process: small GTPase mediated signal transduction; negative regulation of catalytic activity; signal transduction

Research Articles on IQGAP2

Similar Products

Product Notes

The IQGAP2 iqgap2 (Catalog #AAA8307001) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IQGAP2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's IQGAP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the IQGAP2 iqgap2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IQGAP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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