Rabbit CRCP Polyclonal Antibody | anti-CRCP antibody
Anti-CRCP Antibody
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a membrane protein that functions as part of a receptor complex for a small neuropeptide that increases intracellular cAMP levels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Uniprot Description
CGRP-RCP: an ubiquitous coupling protein for the calcitonin gene-related peptide (CGRP) and adrenomedullin receptors. Modulates ligand responsiveness in a variety of tissues. Two splice-variant isoforms have been described.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 7q11.21
Cellular Component: nucleoplasm; DNA-directed RNA polymerase III complex; plasma membrane; acrosome; cytosol
Molecular Function: calcitonin gene-related polypeptide receptor activity; DNA-directed RNA polymerase activity; nucleotide binding
Biological Process: transcription from RNA polymerase III promoter; transcription initiation from RNA polymerase III promoter; termination of RNA polymerase III transcription; neuropeptide signaling pathway; positive regulation of interferon type I production; innate immune response; gene expression; defense response to virus; RNA elongation from RNA polymerase III promoter