RTN4RL1 recombinant protein

Recombinant Human RTN4RL1 Protein

Cat. Num. AAA8249716

• Gene Names: RTN4RL1; NgR3; NGRH2
• Reactivity: Human
• Applications: ELISA, Western Blot, SDS-Page
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Synonyms: RTN4RL1; Recombinant Human RTN4RL1 Protein; NGRH2; NGRL2; Reticulon-4 receptor-like 1; Nogo receptor-like 2; Nogo-66 receptor homolog 2; Nogo-66 receptor-related protein 3; NgR3; RTN4RL1 recombinant protein

• Host: Human cells
• Reactivity: Human
• Purity/Purification: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 muM filtered solution of 20mM PB, 150mM NaCl, 5% Threhalose, pH 7.2
• Sequence: CPRDCVCYPA PMTVSCQAHN FAAIPEGIPV DSERVFLQNN RIGLLQPGHF SPAMVTLWIY SNNITYIHPS TFEGFVHLEE LDLGDNRQLR TLAPETFQGL VKLHALYLYK CGLSALPAGV FGGLHSLQYL YLQDNHIEYL QDDIFVDLVN LSHLFLHGNK LWSLGPGTFR GLVNLDRLLL HENQLQWVHH KAFHDLRRLT TLFLFNNSLS ELQGECLAPL GALEFLRLNG NPWDCGCRAR SLWEWLQRFR GSSSAVPCVS PGLRHGQDLK LLRAEDFRNC TGPASPHQIK SHTLTTTDRA ARKEHHSPHG PTRSKGHPHG PRPGHRKPGK NCTNPRNRNQ ISKAGAGKQA PELPDYAPDY QHKFSFDIMP TARPKRKGKC ARRTPIRAPS GVQQAVDHHH HHH
• Sequence Length: 441

• Applicable Applications for RTN4RL1 recombinant protein: ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
• Endotoxin: Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
• Directions for Use: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Preparation and Storage: Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.

Related Product Information for RTN4RL1 recombinant protein

Recombinant Human RTN4RL1 Protein is produced by our Mammalian expression system and the target gene encoding Cys25-Ala419 is expressed with a 6His tag at the C-terminus.

NCBI and Uniprot Product Information

• NCBI GI #: 30425553
• NCBI GeneID: 146760
• NCBI Accession #: NP_848663.1
• NCBI GenBank Nucleotide #: NM_178568.3
• UniProt Accession #: Q86UN2; Q8ND46; A1A5E3
• Molecular Weight: 49,065 Da
• NCBI Official Full Name: reticulon-4 receptor-like 1
• NCBI Official Synonym Full Names: reticulon 4 receptor like 1
• NCBI Official Symbol: RTN4RL1
• NCBI Official Synonym Symbols: NgR3; NGRH2
• NCBI Protein Information: reticulon-4 receptor-like 1
• UniProt Protein Name: Reticulon-4 receptor-like 1
• Protein Family: Reticulon-4 receptor
• UniProt Gene Name: RTN4RL1
• UniProt Synonym Gene Names: NgR3
• UniProt Entry Name: R4RL1_HUMAN

Uniprot Description

RTN4RL1: May play a role in regulating axonal regeneration and plasticity in the adult central nervous system. Belongs to the Nogo receptor family.

Protein type: Membrane protein, GPI anchor; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: anchored to plasma membrane; cell surface; cytoplasm

Molecular Function: protein binding; protein kinase inhibitor activity; receptor activity

Biological Process: axon regeneration; cytokine and chemokine mediated signaling pathway; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity