FABP7 recombinant protein

Recombinant Human FABP7 Protein

Cat. Num. AAA8249011

• Gene Names: FABP7; MRG; BLBP; FABPB; B-FABP
• Reactivity: Human
• Applications: ELISA, Western Blot, SDS-Page
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Synonyms: FABP7; Recombinant Human FABP7 Protein; BLBP; FABPB; MRG; Fatty acid-binding protein; brain; Brain lipid-binding protein; Brain-type fatty acid-binding protein; B-FABP; Fatty acid-binding protein 7; Mammary-derived growth inhibitor related; FABP7 recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 muM filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
• Sequence: MGSSHHHHHH SSGLVPRGSH MVEAFCATWK LTNSQNFDEY MKALGVGFAT RQVGNVTKPT VIISQEGDKV VIRTLSTFKN TEISFQLGEE FDETTADDRN CKSVVSLDGD KLVHIQKWDG KETNFVREIK DGKMVMTLTF GDVVAVRHYE KA
• Sequence Length: 166

• Applicable Applications for FABP7 recombinant protein: ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
• Endotoxin: Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
• Directions for Use: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Preparation and Storage: Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.

Related Product Information for FABP7 recombinant protein

Recombinant Human FABP7 Protein is produced by our E Coli expression system and the target gene encoding Val2-Ala132 is expressed with a 6His tag at the N-terminus.

NCBI and Uniprot Product Information

• NCBI GI #: 975830154
• NCBI GeneID: 2173
• NCBI Accession #: NP_001305968.1
• NCBI GenBank Nucleotide #: NM_001319039.1
• UniProt Accession #: O15540; O14951; Q6IAU7; Q9H047; B2R4L1
• Molecular Weight: 18,829 Da
• NCBI Official Full Name: fatty acid-binding protein, brain isoform 2
• NCBI Official Synonym Full Names: fatty acid binding protein 7
• NCBI Official Symbol: FABP7
• NCBI Official Synonym Symbols: MRG; BLBP; FABPB; B-FABP
• NCBI Protein Information: fatty acid-binding protein, brain
• UniProt Protein Name: Fatty acid-binding protein, brain
• Protein Family: Fatty acid-binding protein
• UniProt Gene Name: FABP7
• UniProt Synonym Gene Names: BLBP; FABPB; MRG; BLBP; B-FABP
• UniProt Entry Name: FABP7_HUMAN

NCBI Description

The gene encodes a small, highly conserved cytoplasmic protein that bind long-chain fatty acids and other hydrophobic ligands. The encoded protein is important in the establishment of the radial glial fiber in the developing brain. Alternative splicing and promoter usage results in multiple transcript variants encoding different isoforms. Pseudogenes of this gene are found on multiple chromosomes. [provided by RefSeq, Jan 2016]

Uniprot Description

FABP7: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

Protein type: Cell cycle regulation; Cell development/differentiation; Lipid-binding

Chromosomal Location of Human Ortholog: 6q22-q23

Cellular Component: cytoplasm; cytosol; nucleoplasm

Biological Process: negative regulation of cell proliferation; nervous system development; triacylglycerol catabolic process