Western Blot (WB)
(Western blot analysis of Adenylate Cyclase 4 expression in HeLa (A), Jurkat (B), SP2/0 (C), PC12 (D) whole cell lysates.)
Rabbit Adenylate Cyclase 4 Polyclonal Antibody | anti-ADCY4 antibody
Anti-Adenylate Cyclase 4 Antibody
Western Blot (WB)
(Western blot analysis of Adenylate Cyclase 4 expression in HeLa (A), Jurkat (B), SP2/0 (C), PC12 (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Adenylate Cyclase 4 expression in HeLa (A), Jurkat (B), SP2/0 (C), PC12 (D) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). Mouse studies show that adenylate cyclase 4, along with adenylate cyclases 2 and 3, is expressed in olfactory cilia, suggesting that several different adenylate cyclases may couple to olfactory receptors and that there may be multiple receptor-mediated mechanisms for the generation of cAMP signals. Alternative splicing results in transcript variants. [provided by RefSeq, Nov 2010]
Uniprot Description
ADCY4: This is a membrane-bound, calmodulin-insensitive adenylyl cyclase. Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
Protein type: Transporter; Adenylyl cyclase; Membrane protein, multi-pass; Membrane protein, integral; Lyase; Nucleotide Metabolism - purine; EC 4.6.1.1; Transporter, aquaporin family
Chromosomal Location of Human Ortholog: 14q12
Cellular Component: membrane; dendrite; cytoplasm; integral to membrane; plasma membrane
Molecular Function: protein binding; metal ion binding; ATP binding; adenylate cyclase activity
Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; water transport; activation of protein kinase A; signal transduction; G-protein signaling, adenylate cyclase activating pathway; G-protein signaling, coupled to cAMP nucleotide second messenger; synaptic transmission; phospholipase C activation; energy reserve metabolic process; innate immune response; renal water homeostasis; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport
Research Articles on ADCY4
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Product Notes
The ADCY4 adcy4 (Catalog #AAA8237562) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Adenylate Cyclase 4 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Adenylate Cyclase 4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the ADCY4 adcy4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Adenylate Cyclase 4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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