CHD5 blocking peptide
CHD5 Blocking Peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the chromodomain helicase DNA-binding protein family. Members of this family are characterized by a chromodomain, a helicase ATP-binding domain and an additional functional domain. This gene encodes a neuron-specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma. [provided by RefSeq, Feb 2012]
Uniprot Description
CHD-5: May play a role in the development of the nervous system and the pathogenesis of neural tumors. Belongs to the SNF2/RAD54 helicase family.
Protein type: EC 3.6.4.12; Tumor suppressor; DNA-binding; Helicase
Chromosomal Location of Human Ortholog: 1p36.31
Cellular Component: heterochromatin; membrane; NuRD complex; nucleus
Molecular Function: DNA binding; zinc ion binding; ATP-dependent helicase activity; ATP binding
Biological Process: transcription from RNA polymerase II promoter; negative regulation of cell proliferation; spermatogenesis, exchange of chromosomal proteins; cerebral cortex neuron differentiation
Research Articles on CHD5
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Product Notes
The CHD5 chd5 (Catalog #AAA822893) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The CHD5 Blocking Peptide reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's CHD5 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the CHD5 chd5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CHD5, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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