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IARS2 blocking peptide

IARS2 Blocking Peptide

Gene Names
IARS2; ILERS
Reactivity
Human, Mouse, Rat, Monkey
Applications
Blocking (BL)
Purity
>85%
Synonyms
IARS2; IARS2 Blocking Peptide; Isoleucine--tRNA ligase; mitochondrial; Isoleucyl-tRNA synthetase; IleRS; IARS2 blocking peptide
Ordering
For Research Use Only!
Host
Synthetic
Reactivity
Human, Mouse, Rat, Monkey
Purity/Purification
>85%
Form/Format
Lyophilized powder
Sequence Length
1012
Applicable Applications for IARS2 blocking peptide
Blocking (BL)
Application Notes
Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
Quality Control
The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for IARS2 blocking peptide
The peptide is used to block Anti-IARS2 Antibody reactivity.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
113,792 Da
NCBI Official Full Name
isoleucine--tRNA ligase, mitochondrial
NCBI Official Synonym Full Names
isoleucyl-tRNA synthetase 2, mitochondrial
NCBI Official Symbol
IARS2
NCBI Official Synonym Symbols
ILERS
NCBI Protein Information
isoleucine--tRNA ligase, mitochondrial; isoleucine tRNA ligase 2, mitochondrial; isoleucyl-tRNA synthetase, mitochondrial; mitochondrial isoleucine tRNA synthetase; isoleucine-tRNA synthetase 2, mitochondrial
UniProt Protein Name
Isoleucine--tRNA ligase, mitochondrial
UniProt Gene Name
IARS2
UniProt Synonym Gene Names
IleRS
UniProt Entry Name
SYIM_HUMAN

NCBI Description

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of isoleucine-tRNA synthetase exist, a cytoplasmic form and a mitochondrial form. This gene encodes the mitochondrial isoleucine-tRNA synthetase which belongs to the class-I aminoacyl-tRNA synthetase family. [provided by RefSeq, Dec 2014]

Uniprot Description

IARS2: Belongs to the class-I aminoacyl-tRNA synthetase family.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Translation; EC 6.1.1.5; Ligase; Mitochondrial

Chromosomal Location of Human Ortholog: 1q41

Cellular Component: mitochondrion; mitochondrial matrix; cytoplasm; cytosol

Molecular Function: ATP binding; isoleucine-tRNA ligase activity

Biological Process: isoleucyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; mitochondrial translation; regulation of translational fidelity; gene expression

Disease: Cataracts, Growth Hormone Deficiency, Sensory Neuropathy, Sensorineural Hearing Loss, And Skeletal Dysplasia

Research Articles on IARS2

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Product Notes

The IARS2 iars2 (Catalog #AAA822623) is a Blocking Peptide produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The IARS2 Blocking Peptide reacts with Human, Mouse, Rat, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's IARS2 can be used in a range of immunoassay formats including, but not limited to, Blocking (BL). Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours. Researchers should empirically determine the suitability of the IARS2 iars2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IARS2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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