HSPA13 sirna

HSPA13 siRNA (Human)

Cat. Num. AAA8216343

• Gene Names: HSPA13; STCH
• Reactivity: Human
• Applications: RNA Interference (RNAi)
• Purity: > 97%
• Synonyms: HSPA13; HSPA13 siRNA (Human); STCH; Heat shock 70 kDa protein 13; Microsomal stress-70 protein ATPase core; Stress-70 protein chaperone microsome-associated 60 kDa protein; HSPA13 sirna

• Host: Synthetic
• Reactivity: Human
• Specificity: HSPA13 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
• Purity/Purification: > 97%
• Form/Format: Lyophilized powder
• Sequence Length: 471

• Applicable Applications for HSPA13 sirna: RNA Interference (RNAi)
• Quality Control: Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
• Directions for Use: We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
• Components: We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human HSPA13 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for HSPA13 sirna

siRNA to inhibit HSPA13 expression using RNA interference

NCBI and Uniprot Product Information

• NCBI GI #: 48928056
• NCBI GeneID: 6782
• NCBI Accession #: NP_008879.3
• NCBI GenBank Nucleotide #: NM_006948.4
• UniProt Accession #: P48723; Q8NE40; B2R616
• Molecular Weight: 51,927 Da
• NCBI Official Full Name: heat shock 70 kDa protein 13
• NCBI Official Synonym Full Names: heat shock protein 70kDa family, member 13
• NCBI Official Symbol: HSPA13
• NCBI Official Synonym Symbols: STCH
• NCBI Protein Information: heat shock 70 kDa protein 13
• UniProt Protein Name: Heat shock 70 kDa protein 13
• Protein Family: Heat shock 70 kDa protein
• UniProt Gene Name: HSPA13
• UniProt Synonym Gene Names: STCH
• UniProt Entry Name: HSP13_HUMAN

NCBI Description

The protein encoded by this gene is a member of the heat shock protein 70 family and is found associated with microsomes. Members of this protein family play a role in the processing of cytosolic and secretory proteins, as well as in the removal of denatured or incorrectly-folded proteins. The encoded protein contains an ATPase domain and has been shown to associate with a ubiquitin-like protein. [provided by RefSeq, Jul 2008]

Uniprot Description

HSPA13: Has peptide-independent ATPase activity. Belongs to the heat shock protein 70 family.

Protein type: Heat shock protein

Chromosomal Location of Human Ortholog: 21q11

Cellular Component: intracellular membrane-bound organelle; endoplasmic reticulum

Molecular Function: ATP binding