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Immunohistochemistry (IHC) (Anti-GLP2R antibody IHC of human small intestine, intraepithelial neuroendocrine cells and enterocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Rabbit GLP2R / Glp-2 Polyclonal Antibody | anti-GLP2R antibody

Rabbit Polyclonal to Human GLP2R / Glp-2

Reactivity
Human
Predicted Reactivity: Gorilla, Gibbon, Monkey (at least 90% immunogen sequence identity)
Applications
Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
GLP2R / Glp-2; Polyclonal Antibody; Rabbit Polyclonal to Human GLP2R / Glp-2; Anti-GLP2R / Glp-2 Antibody (C-Terminus) IHC-plus; GLP2R; Glp-2; GLP-2-R; GLP-2 receptor; GLP-2R; Glp2 receptor; Human GLP2R; anti-GLP2R antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Predicted Reactivity: Gorilla, Gibbon, Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Specificity
Human GLP2R. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS, 0.1% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
553
Applicable Applications for anti-GLP2R antibody
Immunohistochemistry (IHC - Paraffin)
Application Notes
IHC-P (10 ug/ml)
Target Species
Human
Immunogen Description
Synthetic 16 amino acid peptide from C-terminus of human GLP2R. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey (94%); Marmoset, Hamster (88%); Mouse, Horse (81%).
Immunogen Type
Synthetic peptide
Immunogen
GLP2R / Glp-2 antibody was raised against synthetic 16 amino acid peptide from C-terminus of human GLP2R. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Gibbon, Monkey (94%); Marmoset, Hamster (88%); Mouse, Horse (81%).
Antigen Modification
C-Terminus
Preparation and Storage
Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-GLP2R antibody IHC of human small intestine, intraepithelial neuroendocrine cells and enterocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-GLP2R antibody IHC of human small intestine, intraepithelial neuroendocrine cells and enterocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-GLP2R / Glp-2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC) (Anti-GLP2R / Glp-2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Related Product Information for anti-GLP2R antibody
GLP2R, a Glucagon Receptor, is closely related to the Glucagon Receptor and to the GLP1 Receptor. The glucagon-like peptides (GLP-1 and GLP-2) are proglucagon-derived peptides cosecreted from gut endocrine cells in response to nutrient ingestion. The actions of GLP-2 are mediated by the GLP-2 receptor expressed on subsets of enteric nerves and enteroendocrine cells in the stomach and small and large intestine.
Product Categories/Family for anti-GLP2R antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
63,001 Da
NCBI Official Full Name
glucagon-like peptide 2 receptor
NCBI Official Synonym Full Names
glucagon-like peptide 2 receptor
NCBI Official Symbol
GLP2R
NCBI Protein Information
glucagon-like peptide 2 receptor; GLP-2 receptor
UniProt Protein Name
Glucagon-like peptide 2 receptor
UniProt Gene Name
GLP2R
UniProt Synonym Gene Names
GLP-2 receptor; GLP-2-R; GLP-2R
UniProt Entry Name
GLP2R_HUMAN

NCBI Description

This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014]

Uniprot Description

GLP2R: This is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 2 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 2

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; glucagon receptor activity

Biological Process: G-protein signaling, coupled to cAMP nucleotide second messenger; positive regulation of cell proliferation

Research Articles on GLP2R

Similar Products

Product Notes

The GLP2R glp2r (Catalog #AAA243266) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human GLP2R / Glp-2 reacts with Human Predicted Reactivity: Gorilla, Gibbon, Monkey (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. AAA Biotech's GLP2R / Glp-2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin). IHC-P (10 ug/ml). Researchers should empirically determine the suitability of the GLP2R glp2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "GLP2R / Glp-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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